FXa-IN-1
Modify Date: 2025-11-11 20:23:57
FXa-IN-1 structure
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Common Name | FXa-IN-1 | ||
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| CAS Number | 441328-10-5 | Molecular Weight | 487.42500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H18F5N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FXa-IN-1FXa-IN-1 is a FXa inhibitor (IC50: 3 nM, Ki: 0.7 nM) with respectable oral bioavailability and half-life in vivo. FXa-IN-1 can be used for thromboembolic disorders[1]. |
| Name | N-{4-[(E)-(Dimethylhydrazono)methyl]-2-fluorophenyl}-1-(3-fluoro- 2-naphthyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide |
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| Description | FXa-IN-1 is a FXa inhibitor (IC50: 3 nM, Ki: 0.7 nM) with respectable oral bioavailability and half-life in vivo. FXa-IN-1 can be used for thromboembolic disorders[1]. |
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| Related Catalog | |
| Target |
FXa[1] |
| In Vivo | FXa-IN-1 (compound 22, rats) exhibits good oral bioavailability (F%: 46.9) and half-life (t1/2: 8.8 h, i.v.)[1]. |
| References |
| Molecular Formula | C24H18F5N5O |
|---|---|
| Molecular Weight | 487.42500 |
| Exact Mass | 487.14300 |
| PSA | 66.01000 |
| LogP | 5.85430 |
| InChIKey | BCJOZCDXPVWFLD-VVEOGCPPSA-N |
| SMILES | CN(C)N=Cc1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cc3ccccc3cc2F)c(F)c1 |