ZnAF-1F
Modify Date: 2025-08-26 21:56:55
ZnAF-1F structure
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Common Name | ZnAF-1F | ||
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| CAS Number | 443302-08-7 | Molecular Weight | 608.59100 | |
| Density | 1.49g/cm3 | Boiling Point | 822.1ºC at 760 mmHg | |
| Molecular Formula | C34H26F2N4O5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 451ºC | |
Use of ZnAF-1FZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn2+ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm[1][2][3]. |
| Name | 5-[2-[bis(pyridin-2-ylmethyl)amino]ethylamino]-2-(2,7-difluoro-3-hydroxy-6-oxoxanthen-9-yl)benzoic acid |
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| Synonym | More Synonyms |
| Description | ZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn2+ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm[1][2][3]. |
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| Related Catalog | |
| In Vitro | ZnAF-1F (1 µM) shows an Kon value of 3.5*106 M-1s-1, and an Koff value of 7.7*10-3 s-1 in 100mM HEPES buffer[1]. ZnAF-1F is a Zn sensors in neutral and slightly acidic conditions[2]. |
| References |
[2]. Zhaohua Dai, et al. Tailoring tripodal ligands for zinc sensing. New J. Chem., 2007,31, 1708-1718. |
| Density | 1.49g/cm3 |
|---|---|
| Boiling Point | 822.1ºC at 760 mmHg |
| Molecular Formula | C34H26F2N4O5 |
| Molecular Weight | 608.59100 |
| Flash Point | 451ºC |
| Exact Mass | 608.18700 |
| PSA | 128.79000 |
| LogP | 6.22410 |
| Index of Refraction | 1.715 |
| InChIKey | PUDBCJSXTISPOO-UHFFFAOYSA-N |
| SMILES | O=C(O)c1cc(NCCN(Cc2ccccn2)Cc2ccccn2)ccc1-c1c2cc(F)c(=O)cc-2oc2cc(O)c(F)cc12 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Improvement and biological applications of fluorescent probes for zinc, ZnAFs.
J. Am. Chem. Soc. 124 , 6555-6562, (2002) The development and cellular applications of novel fluorescent probes for Zn2+, ZnAF-1F, and ZnAF-2F are described. Fluorescein is used as a fluorophore of ZnAFs, because its excitation and emission w... |
| ZnAF-1F |
| 5-{2-[Bis(2-pyridylmethyl)amino]ethylamino}-2',7'-difluorofluorescein |