Cdk1/2 Inhibitor III

Modify Date: 2024-01-15 19:57:20

Cdk1/2 Inhibitor III Structure
Cdk1/2 Inhibitor III structure
Common Name Cdk1/2 Inhibitor III
CAS Number 443798-55-8 Molecular Weight 425.43600
Density N/A Boiling Point N/A
Molecular Formula C15H13F2N7O2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cdk1/2 Inhibitor III


Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor, with an IC50 of 2.1 μM for CDK1/cyclin B[1].

 Names

Name 5-amino-N-(2,6-difluorophenyl)-3-(4-sulfamoylanilino)-1,2,4-triazole-1-carbothioamide
Synonym More Synonyms

 Cdk1/2 Inhibitor III Biological Activity

Description Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor, with an IC50 of 2.1 μM for CDK1/cyclin B[1].
Related Catalog
Target

Cdk1/cyclin B:2.1 μM (IC50)

In Vitro Cdk1/2 Inhibitor III has weak CDK1 and cellular antiproliferative potencies[1].
References

[1]. Lin R, et al. Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities. J Med Chem. 2005 Jun 30;48(13):4208-11.

 Chemical & Physical Properties

Molecular Formula C15H13F2N7O2S2
Molecular Weight 425.43600
Exact Mass 425.05400
PSA 189.19000
LogP 3.77930

 Synonyms

CDK 1/2 INHIBITOR
Cdk1/2 Inhibitor III
HMS3229C16
2wu6
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