Lenalidomide-4-aminomethyl hydrochloride structure
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Common Name | Lenalidomide-4-aminomethyl hydrochloride | ||
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CAS Number | 444289-05-8 | Molecular Weight | 309.75 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C14H16ClN3O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Lenalidomide-4-aminomethyl hydrochlorideLenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1] |
Name | Lenalidomide-4-aminomethyl hydrochloride |
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Synonym | More Synonyms |
Description | Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1] |
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Related Catalog | |
Target |
Cereblon |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
References |
Molecular Formula | C14H16ClN3O3 |
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Molecular Weight | 309.75 |
Hazard Codes | Xi |
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MFCD32703223 |