2-Amino-5-fluorobenzoic acid

Modify Date: 2024-01-02 11:21:08

2-Amino-5-fluorobenzoic acid Structure
2-Amino-5-fluorobenzoic acid structure
Common Name 2-Amino-5-fluorobenzoic acid
CAS Number 446-08-2 Molecular Weight 155.13
Density 1.4±0.1 g/cm3 Boiling Point 318.2±27.0 °C at 760 mmHg
Molecular Formula C7H6FNO2 Melting Point 181-183 °C(lit.)
MSDS Chinese USA Flash Point 146.2±23.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-Amino-5-fluorobenzoic acid


2-Amino-5-fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 5-fluoroanthranilic acid
Synonym More Synonyms

 2-Amino-5-fluorobenzoic acid Biological Activity

Description 2-Amino-5-fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 2-Amino-5-fluorobenzoic acid 是酵母中色氨酸通路的一种有毒抗代谢物,可用于反选择 TRP1,TRP1 是酿酒酵母中常用的遗传标记。由于此 trp1 菌株缺乏将蒽苯甲酸转化为色氨酸所需的酶,因此它对 2-amino-5-fluorobenzoic acid 反馈抑制具有抗性,从而能够对 TRP1 标记进行基于生长的阳性选择。2-氨基-5-氟苯甲酸经常用于涉及血浆操纵计算的遗传程序。

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 318.2±27.0 °C at 760 mmHg
Melting Point 181-183 °C(lit.)
Molecular Formula C7H6FNO2
Molecular Weight 155.13
Flash Point 146.2±23.7 °C
Exact Mass 155.038254
PSA 63.32000
LogP 1.64
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.606
Storage condition Room temperature.

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922499990

 Synthetic Route

~98%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: AVANIR PHARMACEUTICALS Patent: WO2004/74218 A2, 2004 ; Location in patent: Page 106 ;

~93%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: Karthikeyan; Jagadeesh, Rajenahally V.; Sree Sandhya; Puttaswamy; Nithya; Kumar, S. Senthil; Bhagat Applied Organometallic Chemistry, 2011 , vol. 25, # 1 p. 34 - 46

~99%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: Hoechst Aktiengesellschaft Patent: US5523472 A1, 1996 ;

~24%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: Uchikawa, Osamu; Mitsui, Keita; Asakawa, Akiko; Morimoto, Shigeru; Yamamoto, Masataka; Kimura, Hiroyuki; Moriya, Takeo; Mizuno, Masahiro Patent: US2003/187014 A1, 2003 ;

~%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: Pokhodylo, Nazariy T.; Matiychuk, Vasyl S. Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 2 p. 415 - 420

~%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: Holt; Sadler Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958 , vol. 148, p. 481,488

~%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: Rajsner; Metysova; Svatek; et al. Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 3 p. 719 - 737

~%

2-Amino-5-fluorobenzoic acid Structure

2-Amino-5-fluor...

CAS#:446-08-2

Literature: Rajsner; Metysova; Svatek; et al. Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 3 p. 719 - 737

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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 Synonyms

2-Amino-5-fluorobenzoic
5-Fluoroanthranilic acid
AURORA KA-5382
RARECHEM AL BO 2236
ZR DF BVQ
EINECS 207-159-7
5-FAA
5-Fluoroanthanilic acid
5-fluoro-2-aminobenzoic acid
MFCD00055566
2-aMino-5-fluorobenzoic aicd
2-amino-5-fluoro-benzoic acid
Benzoic acid, 2-amino-5-fluoro-
4-fluoroanthranilic acid
2-Amino-5-fluorobenzoic acid
2-Amino-5-fluoro benzoicacid
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