2-Amino-5-fluorobenzoic acid structure
|
Common Name | 2-Amino-5-fluorobenzoic acid | ||
---|---|---|---|---|
CAS Number | 446-08-2 | Molecular Weight | 155.13 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 318.2±27.0 °C at 760 mmHg | |
Molecular Formula | C7H6FNO2 | Melting Point | 181-183 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 146.2±23.7 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of 2-Amino-5-fluorobenzoic acid2-Amino-5-fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
Name | 5-fluoroanthranilic acid |
---|---|
Synonym | More Synonyms |
Description | 2-Amino-5-fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
---|---|
Related Catalog | |
In Vitro | 2-Amino-5-fluorobenzoic acid 是酵母中色氨酸通路的一种有毒抗代谢物,可用于反选择 TRP1,TRP1 是酿酒酵母中常用的遗传标记。由于此 trp1 菌株缺乏将蒽苯甲酸转化为色氨酸所需的酶,因此它对 2-amino-5-fluorobenzoic acid 反馈抑制具有抗性,从而能够对 TRP1 标记进行基于生长的阳性选择。2-氨基-5-氟苯甲酸经常用于涉及血浆操纵计算的遗传程序。 |
Density | 1.4±0.1 g/cm3 |
---|---|
Boiling Point | 318.2±27.0 °C at 760 mmHg |
Melting Point | 181-183 °C(lit.) |
Molecular Formula | C7H6FNO2 |
Molecular Weight | 155.13 |
Flash Point | 146.2±23.7 °C |
Exact Mass | 155.038254 |
PSA | 63.32000 |
LogP | 1.64 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.606 |
Storage condition | Room temperature. |
Symbol |
GHS07 |
---|---|
Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi:Irritant |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36-S37/39 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2922499990 |
~98% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: AVANIR PHARMACEUTICALS Patent: WO2004/74218 A2, 2004 ; Location in patent: Page 106 ; |
~93% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: Karthikeyan; Jagadeesh, Rajenahally V.; Sree Sandhya; Puttaswamy; Nithya; Kumar, S. Senthil; Bhagat Applied Organometallic Chemistry, 2011 , vol. 25, # 1 p. 34 - 46 |
~99% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: Hoechst Aktiengesellschaft Patent: US5523472 A1, 1996 ; |
~24% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: Uchikawa, Osamu; Mitsui, Keita; Asakawa, Akiko; Morimoto, Shigeru; Yamamoto, Masataka; Kimura, Hiroyuki; Moriya, Takeo; Mizuno, Masahiro Patent: US2003/187014 A1, 2003 ; |
~% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: Pokhodylo, Nazariy T.; Matiychuk, Vasyl S. Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 2 p. 415 - 420 |
~% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: Holt; Sadler Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958 , vol. 148, p. 481,488 |
~% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: Rajsner; Metysova; Svatek; et al. Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 3 p. 719 - 737 |
~% 2-Amino-5-fluor... CAS#:446-08-2 |
Literature: Rajsner; Metysova; Svatek; et al. Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 3 p. 719 - 737 |
Precursor 8 | |
---|---|
DownStream 9 | |
HS Code | 2922499990 |
---|---|
Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
The superoxide dismutases of Candida glabrata protect against oxidative damage and are required for lysine biosynthesis, DNA integrity and chronological life survival.
Microbiology 161 , 300-10, (2015) The fungal pathogen Candida glabrata has a well-defined oxidative stress response, is extremely resistant to oxidative stress and can survive inside phagocytic cells. In order to further our understan... |
|
The Role of Amino Acid Permeases and Tryptophan Biosynthesis in Cryptococcus neoformans Survival.
PLoS ONE 10 , e0132369, (2015) Metabolic diversity is an important factor during microbial adaptation to different environments. Among metabolic processes, amino acid biosynthesis has been demonstrated to be relevant for survival f... |
|
Synthesis and biological evaluation of 2-styrylquinazolin-4(3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization.
J. Med. Chem. 33 , 1721, (1990) A novel series of 2-styrylquinazolin-4(3H-ones which inhibited tubulin polymerization and the growth of L1210 murine leukemia cells was discovered. Extensive structure-activity relationship studies su... |
2-Amino-5-fluorobenzoic |
5-Fluoroanthranilic acid |
AURORA KA-5382 |
RARECHEM AL BO 2236 |
ZR DF BVQ |
EINECS 207-159-7 |
5-FAA |
5-Fluoroanthanilic acid |
5-fluoro-2-aminobenzoic acid |
MFCD00055566 |
2-aMino-5-fluorobenzoic aicd |
2-amino-5-fluoro-benzoic acid |
Benzoic acid, 2-amino-5-fluoro- |
4-fluoroanthranilic acid |
2-Amino-5-fluorobenzoic acid |
2-Amino-5-fluoro benzoicacid |