Coenzyme M
Coenzyme M structure
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Common Name | Coenzyme M | ||
|---|---|---|---|---|
| CAS Number | 45127-11-5 | Molecular Weight | 282.379 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C4H10O6S4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Molecular Formula | C4H10O6S4 |
| Molecular Weight | 282.379 |
| Exact Mass | 281.936005 |
| PSA | 176.10000 |
| LogP | -1.83 |
| Index of Refraction | 1.637 |
| InChIKey | BYUKOOOZTSTOOH-UHFFFAOYSA-N |
| SMILES | O=S(=O)(O)CCSSCCS(=O)(=O)O |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2930909090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~97%
Coenzyme M CAS#:45127-11-5 |
| Literature: Huang, Qiuli; Kochat, Harry; Chen, Xinghai Patent: US2006/63949 A1, 2006 ; Location in patent: Page/Page column 2 ; |
|
~%
Coenzyme M CAS#:45127-11-5 |
| Literature: Danehy,J.P.; Hunter,W.E. Journal of Organic Chemistry, 1967 , vol. 32, # 7 p. 2047 - 2053 |
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~%
Coenzyme M CAS#:45127-11-5 |
| Literature: Fedoseyeva,V.N.; Petrun'kin,V.E. Sov. Prog. Chem. (Engl. Transl.), 1967 , vol. 33, # 6 p. 596 - 597,57 - 58 |
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~%
Coenzyme M CAS#:45127-11-5 |
| Literature: Lemaire,H.; Rieger,M. Journal of Organic Chemistry, 1961 , vol. 26, p. 1330 - 1331 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N.
Cancer Chemother. Pharmacol. 67(2) , 381-91, (2011) Previous studies from our laboratory have identified a role for gamma-glutamyl transpeptidase (GGT) in BNP7787 (disodium 2,2'-dithio-bis ethane sulfonate, dimesna, Tavocept™)-mediated cisplatin nephro... |
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Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced non-small cell lung cancer (CALGB 30303).
J. Thorac. Oncol. 3(10) , 1159-65, (2008) We investigated dose-dense docetaxel and cisplatin in patients with measurable non-small cell lung cancer in a randomized phase II study without [A] or with [B] a putative chemoprotective agent, BNP77... |
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New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent.
Cancer Chemother. Pharmacol. 52 Suppl 1 , S3-15, (2003) Any approach applied to drug discovery and development by the medical community and pharmaceutical industry has a direct impact on the future availability of improved, novel, and curative therapies fo... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149
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Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2,2'-Dithiodiethanesulfonic acid |
| 2,2'-dithiobisethanesulfonic acid |
| Ethanesulfonic acid,2,2'-dithiobis |
| 2,2'-Disulfanediyldiethanesulfonic acid |
| Coenzyme |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: Related upstream materials(CAS) of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid: 19767-45-4;4263-52-9;3375-50-6. |
| Q: What is the molecular weight of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: Molecular weight of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is 282.379. |
| Q: What is the SMILES notation of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: SMILES notation of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is O=S(=O)(O)CCSSCCS(=O)(=O)O. |
| Q: What is the molecular formula of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: Molecular formula of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is C4H10O6S4. |
| Q: What is the English name of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: The English name of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid. |
| Q: What is the InChIKey of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: InChIKey of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is BYUKOOOZTSTOOH-UHFFFAOYSA-N. |
| Q: What is the polar surface area (PSA) of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: Polar surface area (PSA) of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is 176.10000. |
| Q: What English synonyms does 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid have? |
| A: English synonyms of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid: 2,2'-Dithiodiethanesulfonic acid, 2,2'-dithiobisethanesulfonic acid, Ethanesulfonic acid,2,2'-dithiobis, 2,2'-Disulfanediyldiethanesulfonic acid, Coenzyme. |
| Q: What is the CAS number of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: CAS number of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is 45127-11-5. |
| Q: What is the LogP of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid? |
| A: LogP of 2-(2-sulfoethyldisulfanyl)ethanesulfonic acid is -1.83. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |