2-fluoro-4-methyl-aniline

Modify Date: 2025-08-22 23:23:10

2-fluoro-4-methyl-aniline structure	Common Name	2-fluoro-4-methyl-aniline
	CAS Number	452-80-2	Molecular Weight	125.144
	Density	1.1±0.1 g/cm3	Boiling Point	196.5±0.0 °C at 760 mmHg
	Molecular Formula	C₇H₈FN	Melting Point	3 °C
	MSDS	Chinese USA	Flash Point	79.4±0.0 °C
	Symbol	GHS06	Signal Word	Danger

Name	2-Fluoro-4-Methylaniline
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	196.5±0.0 °C at 760 mmHg
Melting Point	3 °C
Molecular Formula	C₇H₈FN
Molecular Weight	125.144
Flash Point	79.4±0.0 °C
Exact Mass	125.064079
PSA	26.02000
LogP	1.73
Vapour Pressure	0.4±0.3 mmHg at 25°C
Index of Refraction	1.542

2-fluoro-4-methyl-aniline MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XU6650000

CHEMICAL NAME :: p-Toluidine, 2-fluoro-

CAS REGISTRY NUMBER :: 452-80-2

BEILSTEIN REFERENCE NO. :: 2637578

LAST UPDATED :: 199707

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H8-F-N

MOLECULAR WEIGHT :: 125.16

WISWESSER LINE NOTATION :: ZR BF D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H311-H315-H319-H331-H335
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338-P311
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R23/24/25;R36/37/38
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
RTECS	XU6650000
Packaging Group	III
Hazard Class	6.1
HS Code	2921430090

3-Fluoro-4-nitr...

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2-fluoro-4-meth...

CAS#:452-80-2

Literature: Ostaszynski Bl.Soc.Sci.Lett.Lodz, 1952 , vol. <3>3, # 15 p. 6

4-Bromo-3-fluor...

CAS#:452-74-4

~93%

2-fluoro-4-meth...

CAS#:452-80-2

Literature: Ji, Pengju; Atherton, John H.; Page, Michael I. Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7471 - 7478

3-Fluorotoluene

CAS#:352-70-5

2-fluoro-4-meth...

CAS#:452-80-2

Literature: Tomcufcik,A.S.; Seeger,D.R. Journal of Organic Chemistry, 1961 , vol. 26, p. 3351 - 3356

Precursor 3
CAS#:446-34-4 3-Fluoro-4-nitr... CAS#:452-74-4 4-Bromo-3-fluor... CAS#:352-70-5 3-Fluorotoluene
DownStream 10
CAS#:452-81-3 2-Fluoro-4-meth... CAS#:452-79-9 3-Fluoro-4-iodo... CAS#:18349-09-2 2-Bromo-6-fluor... CAS#:27018-16-2 7-methylquinazo...
CAS#:85070-67-3 2-Fluoro-4-meth... CAS#:518070-28-5 2-FLUORO-4-METH... CAS#:122509-72-2 6-Chloro-5-fluo... CAS#:326-67-0 N-(2-fluoro-4-m...
CAS#:146137-80-6 2-Fluoro-4-meth... CAS#:366-45-0 2-Chloro-N-(2-f...

HS Code	2921430090
Summary	HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synthesis of chiral building blocks for use in drug discovery.

Molecules 9(6) , 405-26, (2004)

In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. Th...

Rat liver microsomal metabolism of 2-halogenated 4-methylanilines.

Xenobiotica 22(12) , 1403-23, (1992)

1. Rat liver microsomal metabolism of 2-fluoro-, 2-chloro- and 2-bromo-4-methylaniline was investigated using h.p.l.c. Metabolites identified include products from side-chain C-hydroxylation (benzyl a...

Indoline derivatives as 5-HT(2C) receptor agonists.

Bioorg. Med. Chem. Lett. 14 , 2367-2370, (2004)

A series of 1-(1-indolinyl)-2-propylamines was synthesised and evaluated as 5-HT(2C) receptor agonists for the treatment of obesity. The general methods of synthesis of the precursor indoles are descr...

4-Amino-3-fluorotoluene

Benzenamine, 2-fluoro-4-methyl-

p-Toluidine, 2-fluoro-

2-Fluoro-4-methylaniline

Aniline, 2-fluoro-4-methyl-

2-Fluoro-4-methyaniline

ZR BF D1

MFCD00040975

EINECS 259-564-3

2-Fluoro-4-methylbenzenamine

2-Fluoro-p-toluidine

2-fluoro-4-methyl-aniline

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-fluoro-4-methyl-aniline
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-fluoro-4-methyl-aniline
Price: ￥348.0/25g ￥108.0/5g
Purity: 99.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Fluoro-4-methylaniline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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2-fluoro-4-methyl-aniline

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.