5-Nitrothiophen-2-carbaldehyd

Modify Date: 2025-08-20 20:14:59

5-Nitrothiophen-2-carbaldehyd Structure
5-Nitrothiophen-2-carbaldehyd structure
Common Name 5-Nitrothiophen-2-carbaldehyd
CAS Number 4521-33-9 Molecular Weight 157.147
Density 1.5±0.1 g/cm3 Boiling Point 297.2±25.0 °C at 760 mmHg
Molecular Formula C5H3NO3S Melting Point 75-77 °C(lit.)
MSDS Chinese USA Flash Point 133.5±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5-Nitrothiophene-2-Carboxaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 297.2±25.0 °C at 760 mmHg
Melting Point 75-77 °C(lit.)
Molecular Formula C5H3NO3S
Molecular Weight 157.147
Flash Point 133.5±23.2 °C
Exact Mass 156.983368
PSA 91.13000
LogP 1.15
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.663
InChIKey CHTSWZNXEKOLPM-UHFFFAOYSA-N
SMILES O=Cc1ccc([N+](=O)[O-])s1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles4

More Articles
Asymmetric hetero-Diels-Alder reaction catalyzed by dirhodium(II) carboxamidates.

Proc. Natl. Acad. Sci. U. S. A. 101(15) , 5391-5, (2004)

Chiral dirhodium(II) carboxamidates are highly efficient catalysts for reactions between a variety of aldehydes and activated dienes. Catalyst loadings as low at 0.01 mol % have been realized with ena...

Antibacterial 2,3-dihydro-2-(5-nitro-2-thienyl)-quinazolin-4(1H)-ones.

J. Med. Chem. 15(3) , 335-6, (1972)

Synthesis and Antimycobacterial Activity of 2-(Phenylthio) benzoylarylhydrazone Derivatives.

Iran. J. Pharm. Res. 10 , 727-31, (2013)

A series of new 2-(phenylthio) benzoylarylhydrazones were synthesized by acid-catalyzed condensation of hydrazide 3 with corresponding aldehydes. The chemical structures of the compounds were elucidat...

 5-Nitrothiophen-2-carbaldehydBioassay

View more

Name: Selectivity index, ratio of IC50 for cytotoxicity against human THP-1 cells assessed ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5330081
Name: Antileishmanial activity against intracellular Leishmania amazonensis MHOM/BR/77/LTB ...
Source: ChEMBL
Target: Leishmania amazonensis
External Id: CHEMBL4825487
Name: Antileishmanial activity against Leishmania infantum MHOM/MA/67/ITMAP-263 promastigot...
Source: ChEMBL
Target: Leishmania infantum
External Id: CHEMBL4825488
Name: Antitrypanosomal activity against bloodstream Trypanosoma cruzi trypomastigotes infec...
Source: ChEMBL
Target: Trypanosoma cruzi
External Id: CHEMBL5330079
Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2
Name: Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cel...
Source: ChEMBL
Target: Peritoneal macrophage
External Id: CHEMBL4825485
Name: Selectivity index, ratio of IC50 for cytotoxicity against African green monkey Vero c...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5330080
Name: Antileishmanial activity against Leishmania amazonensis MHOM/BR/77/LTB 0016 promastig...
Source: ChEMBL
Target: Leishmania amazonensis
External Id: CHEMBL4825486
Name: Antitrypanosomal activity against Trypanosoma cruzi epimastigotes assessed as parasit...
Source: ChEMBL
Target: Trypanosoma cruzi
External Id: CHEMBL5330077
Name: Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse peritoneal mac...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4825505
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 Synonyms

5-nitrothiophene-2-carbaldehyde
5-Nitro-2-thiophenecarbaldehyde
5-Nitrothiophene-2-carboxaldehyde
5-Nitrothiophen-2-carbaldehyd
EINECS 224-850-9
MFCD00005433
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