2-Fluoro-4-nitroanisole

Modify Date: 2025-08-25 18:38:57

2-Fluoro-4-nitroanisole Structure
2-Fluoro-4-nitroanisole structure
Common Name 2-Fluoro-4-nitroanisole
CAS Number 455-93-6 Molecular Weight 171.12600
Density 1.321 g/cm3 Boiling Point 277.2ºC at 760 mmHg
Molecular Formula C7H6FNO3 Melting Point 103-105 °C(lit.)
MSDS Chinese USA Flash Point 121.4ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Fluoro-4-nitroanisole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.321 g/cm3
Boiling Point 277.2ºC at 760 mmHg
Melting Point 103-105 °C(lit.)
Molecular Formula C7H6FNO3
Molecular Weight 171.12600
Flash Point 121.4ºC
Exact Mass 171.03300
PSA 55.05000
LogP 2.26570
Vapour Pressure 0.000519mmHg at 25°C
Index of Refraction 1.552
InChIKey XGMVTXUXZUPGGY-UHFFFAOYSA-N
SMILES COc1ccc([N+](=O)[O-])cc1F

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2909309090

 Synthetic Route

 Customs

HS Code 2909309090
Summary 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles3

More Articles
The element effect and nucleophilicity in nucleophilic aromatic photosubstitution (SN2Ar*). Local atom effects as mechanistic probes of very fast reactions.

J. Org. Chem. 73(5) , 1925-34, (2008)

Photoreactions of 4-nitroanisole and the 2-halo-4-nitroanisoles (halogen = F, Cl, Br, and I) with the nucleophiles hydroxide ion and pyridine have been investigated quantitatively to extend the findin...

The photosubstitution of 2-fluoro-4-nitroanisole with n-hexylamine. Evidence of two different triplet excited states in a dual mechanistic pathway. Pleixats R and Marquet J.

Tetrahedron 46(4) , 1343-52, (1990)

The Search for Biochemical Photoprobes. III. The Photoreactions of 4-Nitroveratrole and 2-Fluoro-4-nitroanisole with Bovine Pancreatic Ribonuclease A and with Model Nucleophiles. Marquet J, et al.

Tetrahedron 49(6) , 1297-1306, (1993)

 2-Fluoro-4-nitroanisoleBioassay

View more

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
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 Synonyms

MFCD00061095
2-Fluoro-1-methoxy-4-nitrobenzene
2-Fluoro-4-Nitroanisole
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