4-Fluorophenylacetyl chloride

Modify Date: 2024-01-08 17:00:08

4-Fluorophenylacetyl chloride Structure
4-Fluorophenylacetyl chloride structure
Common Name 4-Fluorophenylacetyl chloride
CAS Number 459-04-1 Molecular Weight 172.58400
Density 1.259 Boiling Point 60 °C (8 mmHg)
Molecular Formula C8H6ClFO Melting Point 47-48
MSDS Chinese USA Flash Point 107 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 4-Fluorophenylacetyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.259
Boiling Point 60 °C (8 mmHg)
Melting Point 47-48
Molecular Formula C8H6ClFO
Molecular Weight 172.58400
Flash Point 107 °C
Exact Mass 172.00900
PSA 17.07000
LogP 2.13360
Vapour Pressure 0.0884mmHg at 25°C
Index of Refraction 1.511-1.513
Storage condition Store at RT.

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xi: Irritant;C: Corrosive;
Risk Phrases R34
Safety Phrases S45-S36/37/39-S26-S27
RIDADR 3265
Packaging Group II
Hazard Class 8
HS Code 2916399090

 Synthetic Route

~97%

4-Fluorophenylacetyl chloride Structure

4-Fluorophenyla...

CAS#:459-04-1

Literature: Chatterjee, Arnab K.; Liu, Hong; Tully, David C.; Guo, Jianhua; Epple, Robert; Russo, Ross; Williams, Jennifer; Roberts, Michael; Tuntland, Tove; Chang, Jonathan; Gordon, Perry; Hollenbeck, Thomas; Tumanut, Christine; Li, Jun; Harris, Jennifer L. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2899 - 2903

~0%

4-Fluorophenylacetyl chloride Structure

4-Fluorophenyla...

CAS#:459-04-1

Literature: Nissin Food Products Co., Ltd. Patent: US6294568 B1, 2001 ;

~%

4-Fluorophenylacetyl chloride Structure

4-Fluorophenyla...

CAS#:459-04-1

Literature: Pineiro, Jose Luis Castro; Churcher, Ian; Guiblin, Alexander Richard; Harrison, Timothy; Kerrard, Sonia; Madin, Andrew; Nadin, Alan John; Owens, Andrew Pate; Sparey, Timothy Jason; Teall, Martin Richard; Williams, Susannah Patent: US2004/82572 A1, 2004 ;

~%

4-Fluorophenylacetyl chloride Structure

4-Fluorophenyla...

CAS#:459-04-1

Literature: Adcock,W. et al. Australian Journal of Chemistry, 1970 , vol. 23, p. 1921 - 1937

~%

4-Fluorophenylacetyl chloride Structure

4-Fluorophenyla...

CAS#:459-04-1

Literature: Adcock,W. et al. Australian Journal of Chemistry, 1970 , vol. 23, p. 1921 - 1937

~%

4-Fluorophenylacetyl chloride Structure

4-Fluorophenyla...

CAS#:459-04-1

Literature: Adcock,W. et al. Australian Journal of Chemistry, 1970 , vol. 23, p. 1921 - 1937

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles7

More Articles
Synthesis and thromboxane A2 antagonistic activity of [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives.

Chem. Pharm. Bull. 44 , 765, (1996)

In order to find new antiasthmatic and antithrombotic agents, various [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives were synthesized. Evaluation of these compounds ...

Drug Des. Discovery 11 , 115, (1994)

Drug Des. Discovery 9 , 155, (1992)

 Synonyms

MFCD00674181
2-(4-fluorophenyl)acetyl chloride
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