![]() 3a-(3,4-dimethoxyphenyl)-1-methyl-octahydro-1H-indol-6(2H)-one structure
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Common Name | 3a-(3,4-dimethoxyphenyl)-1-methyl-octahydro-1H-indol-6(2H)-one | ||
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CAS Number | 468-53-1 | Molecular Weight | 289.36900 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C17H23NO3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of 3a-(3,4-dimethoxyphenyl)-1-methyl-octahydro-1H-indol-6(2H)-oneMesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a Ki of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC50 of 7.8 μM[1][2]. |
Name | 3a-(3,4-dimethoxyphenyl)-1-methyl-octahydro-1H-indol-6(2H)-one |
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Synonym | More Synonyms |
Description | Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a Ki of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC50 of 7.8 μM[1][2]. |
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Related Catalog | |
Target |
PDE4B:7.8 μM (IC50) serotonin:1.4 nM (Ki) |
In Vitro | Mesembrine can bind to cloned human cannabinoid CB1 receptors in vitro[1]. |
References |
Molecular Formula | C17H23NO3 |
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Molecular Weight | 289.36900 |
Exact Mass | 289.16800 |
PSA | 38.77000 |
LogP | 2.33660 |
Vapour Pressure | 3.09E-07mmHg at 25°C |
Hazard Codes | Xi |
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mesembrine |