Tolbutamide Sodium

Modify Date: 2024-01-11 18:23:16

Tolbutamide Sodium structure	Common Name	Tolbutamide Sodium
	CAS Number	473-41-6	Molecular Weight	270.34800
	Density	1.184g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₈N₂O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tolbutamide Sodium

Tolbutamide sodium is a potent and orally active antidiabetic agent. Tolbutamide sodium induces apoptosis in a Ca2+ dependent manner in pancreatic β-cells. Tolbutamide sodium has the potential for the research of non-insulin-dependent diabetes mellitus[1][2].

Name	sodium,butylcarbamoyl-(4-methylphenyl)sulfonylazanide
Synonym	More Synonyms

Description	Tolbutamide sodium is a potent and orally active antidiabetic agent. Tolbutamide sodium induces apoptosis in a Ca2+ dependent manner in pancreatic β-cells. Tolbutamide sodium has the potential for the research of non-insulin-dependent diabetes mellitus[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Metabolic Disease
References	[1]. Trube G, et al. Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells. Pflugers Arch. 1986 Nov;407(5):493-9. [2]. Efanova IB, et al. Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration. J Biol Chem. 1998 Dec 11;273(50):33501-7.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Metabolic Disease

References

[1]. Trube G, et al. Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells. Pflugers Arch. 1986 Nov;407(5):493-9.

[2]. Efanova IB, et al. Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration. J Biol Chem. 1998 Dec 11;273(50):33501-7.