Epiandrosterone

Modify Date: 2025-08-21 17:48:19

Epiandrosterone Structure
Epiandrosterone structure
Common Name Epiandrosterone
CAS Number 481-29-8 Molecular Weight 290.440
Density 1.1±0.1 g/cm3 Boiling Point 413.1±45.0 °C at 760 mmHg
Molecular Formula C19H30O2 Melting Point 172-174 °C
MSDS USA Flash Point 176.4±21.3 °C

 Use of Epiandrosterone


Epiandrosterone is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA.

 Names

Name epiandrosterone
Synonym More Synonyms

 Epiandrosterone Biological Activity

Description Epiandrosterone is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Mitamura K, et al. Determination of sulfates of androsterone and epiandrosterone in human serum using isotope diluted liquid chromatography-electrospray ionization-mass spectrometry. Biomed Chromatogr. 2005 Dec;19(10):796-801.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 413.1±45.0 °C at 760 mmHg
Melting Point 172-174 °C
Molecular Formula C19H30O2
Molecular Weight 290.440
Flash Point 176.4±21.3 °C
Exact Mass 290.224579
PSA 37.30000
LogP 3.75
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.536
InChIKey QGXBDMJGAMFCBF-LUJOEAJASA-N
SMILES CC12CCC3C(CCC4CC(O)CCC43C)C1CCC2=O
Water Solubility practically insoluble

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2937290090

 Synthetic Route

 Customs

HS Code 2937290090

 Articles6

More Articles
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.

J. Med. Chem. 51 , 1831-41, (2008)

TGR5, a metabotropic receptor that is G-protein-coupled to the induction of adenylate cyclase, has been recognized as the molecular link connecting bile acids to the control of energy and glucose home...

Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.

J. Med. Chem. 52 , 7488-502, (2009)

17beta-Hydroxysteroid dehydrogenase type 7 (17beta-HSD7) catalyzes the reduction of estrone (E(1)) into estradiol (E(2)) and of dihydrotestosterone (DHT) into 5alpha-androstane-3beta,17beta-diol (3bet...

A simple method for the small scale synthesis and solid-phase extraction purification of steroid sulfates.

Steroids 92 , 74-80, (2014)

Steroid sulfates are a major class of steroid metabolite that are of growing importance in fields such as anti-doping analysis, the detection of residues in agricultural produce or medicine. Despite t...

 EpiandrosteroneBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
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 Synonyms

UNII:8TR252Z538
D-epiandrosterone
3β-Hydroxyetioallocholan-17-one
3b-Hydroxy-5a-androstane-17-one
3β-Hydroxy-5α-androstan-17-one
3BETA-HYDROXY-5ALPHA-ANDROSTAN-17-ONE
3b-Androsterone
3b-Androstanol-17-one
EINECS 207-563-3
Epi-androsterone
3β-hydroxy-androstan-17-one
ISOANDROSTERONE
MFCD00064134
epiandrosteron
3b-Hydroxy-17-oxo-5a-androstane
trans-Androsterone
Epiandrosterone
3β-Androsterone
(3β,5α)-3-Hydroxyandrostan-17-one
3B-HYDROXY-5A-ANDROSTAN-17-ONE
(3b,5a)-3-Hydroxyandrostan-17-one
(3S,5S,8R,9S,10S,13S,14S)-3-Hydroxy-10,13-dimethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-one
3b-Hydroxyetioallocholan-17-one
3beta-Androsterone
EPLANDROSTERONE
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