PAZ-417
Modify Date: 2024-04-06 10:36:30
PAZ-417 structure
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Common Name | PAZ-417 | ||
|---|---|---|---|---|
| CAS Number | 481629-87-2 | Molecular Weight | 425.51900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H27NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PAZ-417Aleplasinin is an orally active, potent, BBB-penetrated and selectiveSERPINE1 (PAI-1, Plasminogen activator inhibitor-1) inhibitor. Aleplasinin increases amyloid-β (Aβ) catabolism and ameliorates amyloid-related pathology. Aleplasinin improves memory deficiency. Aleplasinin can be used for Alzheimer's disease research[1][2]. |
| Name | 2-[1-[(4-tert-butylphenyl)methyl]-5-(3-methylphenyl)indol-3-yl]-2-oxoacetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Aleplasinin is an orally active, potent, BBB-penetrated and selectiveSERPINE1 (PAI-1, Plasminogen activator inhibitor-1) inhibitor. Aleplasinin increases amyloid-β (Aβ) catabolism and ameliorates amyloid-related pathology. Aleplasinin improves memory deficiency. Aleplasinin can be used for Alzheimer's disease research[1][2]. |
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| Related Catalog | |
| References |
[1]. Zhao J, Pei G. Evoking plasmin for beta-amyloid clearance. Cell Res. 2008 Aug;18(8):803-4. |
| Molecular Formula | C28H27NO3 |
|---|---|
| Molecular Weight | 425.51900 |
| Exact Mass | 425.19900 |
| PSA | 59.30000 |
| LogP | 6.22980 |
|
~95%
PAZ-417 CAS#:481629-87-2 |
| Literature: Wyeth Patent: US2003/125371 A1, 2003 ; |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| UNII-LL56J87F3X |
| Aleplasinin |
| PAZ-417 |