Diaplasinin
Modify Date: 2024-01-31 17:33:09
Diaplasinin structure
|
Common Name | Diaplasinin | ||
|---|---|---|---|---|
| CAS Number | 481631-45-2 | Molecular Weight | 501.62100 | |
| Density | 1.21g/cm3 | Boiling Point | 759.2ºC at 760mmHg | |
| Molecular Formula | C32H31N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 413ºC | |
Use of DiaplasininDiaplasinin (PAI-749) is a plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 295 nm. Antithrombotic efficacy[1]. |
| Name | 1-benzyl-3-pentyl-2-[6-(2H-tetrazol-5-ylmethoxy)naphthalen-2-yl]indole |
|---|---|
| Synonym | More Synonyms |
| Description | Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 295 nm. Antithrombotic efficacy[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) activities in the presence of PAI-1 (IC50 values, 157 and 87 nM, respectively)[2]. PAI-749 quenches the fluorescence (Fl) of fluorophore-tagged PAI-1 (PAI-NBD119) with the apparent Kd of 254 nM) and the IC50 of 140 nM[2]. |
| References |
| Density | 1.21g/cm3 |
|---|---|
| Boiling Point | 759.2ºC at 760mmHg |
| Molecular Formula | C32H31N5O |
| Molecular Weight | 501.62100 |
| Flash Point | 413ºC |
| Exact Mass | 501.25300 |
| PSA | 68.62000 |
| LogP | 7.33460 |
| Index of Refraction | 1.661 |
| PAI-749 |
| UNII-NRL66AVH63 |
| Diaplasinin |