Nordalbergin
Nordalbergin structure
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Common Name | Nordalbergin | ||
|---|---|---|---|---|
| CAS Number | 482-82-6 | Molecular Weight | 254.238 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 522.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H10O4 | Melting Point | 244ºC | |
| MSDS | N/A | Flash Point | 205.2±23.6 °C | |
Use of NordalberginNordalbergin, a coumarin isolated from the wood bark of Dalbergia sissoo. Nordalbergin shows strong activity in the induction of differentiation of HL-60[1]. |
| Name | 6,7-dihydroxy-4-phenylchromen-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | Nordalbergin, a coumarin isolated from the wood bark of Dalbergia sissoo. Nordalbergin shows strong activity in the induction of differentiation of HL-60[1]. |
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| Related Catalog | |
| References |
[1]. Promyelocytic, leukemia, cells, HL-60, differentiation, coumarin |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 522.4±50.0 °C at 760 mmHg |
| Melting Point | 244ºC |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.238 |
| Flash Point | 205.2±23.6 °C |
| Exact Mass | 254.057907 |
| PSA | 70.67000 |
| LogP | 3.69 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.699 |
| InChIKey | TZRNJQYCOSMOJS-UHFFFAOYSA-N |
| SMILES | O=c1cc(-c2ccccc2)c2cc(O)c(O)cc2o1 |
| Storage condition | 2-8°C |
| HS Code | 2932209090 |
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~46%
Nordalbergin CAS#:482-82-6 |
| Literature: Thaplial, Prakash Chander Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1998 , vol. 37, # 5 p. 477 - 479 |
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Nordalbergin CAS#:482-82-6 |
| Literature: Ahluwalia et al. Proceedings - Indian Academy of Sciences, Section A, 1957 , # 45 p. 293,295 |
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Nordalbergin CAS#:482-82-6 |
| Literature: Ganguly et al. Tetrahedron, 1967 , vol. 23, p. 4777 |
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Nordalbergin CAS#:482-82-6 |
| Literature: Ahluwalia et al. Proceedings - Indian Academy of Sciences, Section A, 1957 , # 45 p. 15,17 |
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Nordalbergin CAS#:482-82-6 |
| Literature: Singh, H. B.; Negi, R. K.; Srivastava, Smita Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical, 1981 , vol. 20, # 10 p. 1026 - 1028 |
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Nordalbergin CAS#:482-82-6 |
| Literature: Kulshrestha, S.K.; Dureja, P.; Mukerjee, S.K. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 11 p. 1064 - 1067 |
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Nordalbergin CAS#:482-82-6 |
| Literature: Ahluwalia et al. Proceedings - Indian Academy of Sciences, Section A, 1957 , # 45 p. 293,295 |
|
~%
Nordalbergin CAS#:482-82-6 |
| Literature: Bargellini; Martegiani Gazzetta Chimica Italiana, 1911 , vol. 41 II, p. 613 |
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~%
Nordalbergin CAS#:482-82-6 |
| Literature: Kulshrestha, S.K.; Dureja, P.; Mukerjee, S.K. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 11 p. 1064 - 1067 |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Name: Reduction of galactitol accumulation in Wistar rat lens after 24 hrs
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1260802
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Name: Selectivity index, ratio of IC50 for human recombinant aldose reductase 1 to IC50 for...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1260801
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|
Name: Selectivity index, ratio of IC50 for sorbitol dehydrogenase to IC50 for kidney aldose...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1260800
|
|
Name: Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 ...
Source: ChEMBL
Target: Induced myeloid leukemia cell differentiation protein Mcl-1
External Id: CHEMBL4705995
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|
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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|
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
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|
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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| 4-phenylesculetin |
| Nordalbergin |
| 6,7-Dihydroxy-4-phenyl-cumarin |
| 6,7-Dihydroxy-4-phenylcoumarin |
| 6,7-Dihydroxy-4-phenyl-2H-chromen-2-one |
| 6,7-dihydroxy-4-phenyl-chromen-2-one |
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