Okanin
Modify Date: 2024-01-14 12:23:10
Okanin structure
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Common Name | Okanin | ||
|---|---|---|---|---|
| CAS Number | 484-76-4 | Molecular Weight | 288.25 | |
| Density | 1.584g/cm3 | Boiling Point | 638ºC at 760mmHg | |
| Molecular Formula | C15H12O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 353.7ºC | |
Use of OkaninOkanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways[1]. |
| Name | okanin |
|---|---|
| Synonym | More Synonyms |
| Description | Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways[1]. |
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| Related Catalog | |
| Target |
TLR4 p65 |
| In Vitro | Okanin significantly inhibits LPS-induced TLR4 expression in BV-2 cells. Okanin inhibits the translocation of the NF-κB p65 subunit from the cytosol to the nucleus. Okanin significantly suppresses LPS-induced iNOS expression and also inhibites IL-6 and TNF-α production and mRNA expression in LPS-stimulated BV-2 cells[1]. |
| References |
| Density | 1.584g/cm3 |
|---|---|
| Boiling Point | 638ºC at 760mmHg |
| Molecular Formula | C15H12O6 |
| Molecular Weight | 288.25 |
| Flash Point | 353.7ºC |
| Exact Mass | 288.06300 |
| PSA | 118.22000 |
| LogP | 2.11070 |
| Vapour Pressure | 7.12E-17mmHg at 25°C |
| Index of Refraction | 1.782 |
| Storage condition | -20 °C |
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Okanin CAS#:484-76-4 |
| Literature: Kurth Journal of the American Chemical Society, 1939 , vol. 61, p. 861 |
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Okanin CAS#:484-76-4 |
| Literature: Russell; Todd Journal of the Chemical Society, 1934 , p. 1506 |
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Okanin CAS#:484-76-4 |
| Literature: Russell; Todd Journal of the Chemical Society, 1934 , p. 1506 |
| 3,4,2',3',4'-Pentahydroxy-trans-chalkon |
| Okanin,2',3,3',4,4'-Pentahydroxychalcone |
| 2',3,3',4,4'-Pentahydroxychalcone |
| OKANIN |
| (E)-3-(3,4-Dihydroxyphenyl)-1-(2,3,4-trihydroxyphenyl)-2-propen-1-one |
| 2',3',4',3,4,-PENTAHYDROXYCHALCONE |
| 2'.3'.4'.3.4-Pentahydroxy-chalkon |
| 3,4,2',3',4'-pentahydroxy-trans-chalcone |