2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one

Modify Date: 2024-01-12 18:59:49

2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one structure	Common Name	2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one
	CAS Number	485-61-0	Molecular Weight	279.29
	Density	1.327g/cm3	Boiling Point	436.7ºC at 760mmHg
	Molecular Formula	C₁₇H₁₃NO₃	Melting Point	204-205 °C
	MSDS	N/A	Flash Point	217.9ºC

Use of 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one

Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].

Name	2-(1,3-benzodioxol-5-yl)-1-methylquinolin-4-one
Synonym	More Synonyms

Description	Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Ghosh S, et, al. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2014 Aug;28(8):1153-62. [2]. Kamal LZM, et, al. Identification of Alkaloid Compounds Arborinine and Graveoline from Ruta angustifolia (L.) Pers for their Antifungal Potential against Isocitrate lyase (ICL1) gene of Candida albicans. Mycopathologia. 2021 May;186(2):221-236.

Description

Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

References

[1]. Ghosh S, et, al. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2014 Aug;28(8):1153-62.

[2]. Kamal LZM, et, al. Identification of Alkaloid Compounds Arborinine and Graveoline from Ruta angustifolia (L.) Pers for their Antifungal Potential against Isocitrate lyase (ICL1) gene of Candida albicans. Mycopathologia. 2021 May;186(2):221-236.

Density	1.327g/cm3
Boiling Point	436.7ºC at 760mmHg
Melting Point	204-205 °C
Molecular Formula	C₁₇H₁₃NO₃
Molecular Weight	279.29
Flash Point	217.9ºC
Exact Mass	279.09000
PSA	40.46000
LogP	2.93420
Vapour Pressure	7.91E-08mmHg at 25°C
Index of Refraction	1.652

Precursor 8
CAS#:83-54-5 1-methylquinoli... CAS#:5876-51-7 1-Iodo-3,4-meth... CAS#:74054-38-9 2-(3,4-methylen... CAS#:74-88-4 methyl iodide
CAS#:6808-65-7 2-(1,3-Benzodio... CAS#:333-27-7 Methyl trifluor... CAS#:120-57-0 piperonal CAS#:2635-13-4 5-Bromo-1,3-ben...
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