485-61-0

485-61-0 structure

Name: 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one
Chemical Name: 2-(1,3-benzodioxol-5-yl)-1-methylquinolin-4-one
CAS Number: 485-61-0
Molecular Formula: C₁₇H₁₃NO₃
Molecular Weight: 279.29
Catalog: Chemical reagent Organic reagent Azide
Create Date: 2016-07-21 21:33:13
Modify Date: 2025-08-25 13:45:46
Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].

Name	2-(1,3-benzodioxol-5-yl)-1-methylquinolin-4-one
Synonyms	1-Methyl-2-<3,4-methylendioxyphenyl>-4-chinolon Graveolin Graveolin od. Rutamin Graveoline Prestwick_165

Description	Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Ghosh S, et, al. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2014 Aug;28(8):1153-62. [2]. Kamal LZM, et, al. Identification of Alkaloid Compounds Arborinine and Graveoline from Ruta angustifolia (L.) Pers for their Antifungal Potential against Isocitrate lyase (ICL1) gene of Candida albicans. Mycopathologia. 2021 May;186(2):221-236.