2,4,6-Trihydroxybenzaldehyde

Modify Date: 2025-08-23 17:53:39

2,4,6-Trihydroxybenzaldehyde structure	Common Name	2,4,6-Trihydroxybenzaldehyde
	CAS Number	487-70-7	Molecular Weight	154.120
	Density	1.6±0.1 g/cm3	Boiling Point	319.1±22.0 °C at 760 mmHg
	Molecular Formula	C₇H₆O₄	Melting Point	195 °C (dec.)(lit.)
	MSDS	USA	Flash Point	161.0±18.8 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2,4,6-Trihydroxybenzaldehyde

2,4,6-Trihydroxybenzaldehyde is an orally active NF-ĸB inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity[1][2][3].

Name	2,4,6-Trihydroxybenzaldehyde
Synonym	More Synonyms

Description	2,4,6-Trihydroxybenzaldehyde is an orally active NF-ĸB inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity[1][2][3].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	2,4,6-Trihydroxybenzaldehyde inhibits adipocyte differentiation and lipid accumulation in 3T3-L1 cells[1]. 2,4,6-Trihydroxybenzaldehyde down-regulates PPARγ, C/EBPα, SREBP-1c, and FAS protein expression levels[1].
In Vivo	2,4,6-Trihydroxybenzaldehyde (oral administration; 5 and 25 mg/kg for 13 weeks) reduces the HFD-induced increase in weight gain, reduces serum levels of glucose, triglycerides, and total cholesterol[1].

Density	1.6±0.1 g/cm3
Boiling Point	319.1±22.0 °C at 760 mmHg
Melting Point	195 °C (dec.)(lit.)
Molecular Formula	C₇H₆O₄
Molecular Weight	154.120
Flash Point	161.0±18.8 °C
Exact Mass	154.026611
PSA	77.76000
LogP	1.37
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.734

2,4,6-Trihydroxybenzaldehyde MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU8440000

CHEMICAL NAME :: Benzaldehyde, 2,4,6-trihydroxy-

CAS REGISTRY NUMBER :: 487-70-7

BEILSTEIN REFERENCE NO. :: 2254429

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H6-O4

MOLECULAR WEIGHT :: 154.13

WISWESSER LINE NOTATION :: VHR BQ DQ FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3200 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P280-P305 + P351 + P338-P337 + P313
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	CU8440000
HS Code	2912499000

HS Code	2912499000
Summary	2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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Tea prepared from the aerial parts of Antigonon leptopus is used as a remedy for cold and pain relief in many countries. In this study, A. leptopus tea, prepared from the dried aerial parts, was evalu...

2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice.

Environ. Toxicol. Pharmacol. 39 , 962-8, (2015)

In the present study, 2,4,6-trihydroxybenzaldehyde (THB) was evaluated for inhibitory effects on adipocyte differentiation in 3T3-L1 cells and anti-obesity effects in mice with high-fat diet (HFD)-ind...

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In red and rosé wines, the grape anthocyanins are progressively converted to more stable pigments, including phenylpyranoanthocyanins. One-/two-dimensional NMR and UPLC-DAD-ESI-MS(n) measurements were...

EINECS 207-663-7

MFCD00003329

Phloroglucinolcarboxaldehyde

Benzaldehyde, 2,4,6-trihydroxy-

2,4,6-Trihydroxybenzaldehyde