guaiazulene

Modify Date: 2025-08-28 12:38:22

guaiazulene structure	Common Name	guaiazulene
	CAS Number	489-84-9	Molecular Weight	198.303
	Density	0.976	Boiling Point	305.4±22.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₁₈	Melting Point	27-29 °C(lit.)
	MSDS	N/A	Flash Point	142.3±13.1 °C

Use of guaiazulene

Guaiazulene is present in several essential oils of medicinal and aromatic plants, with antioxidant activity. Guaiazulene has in vitro cytotoxic activity against neuron and N2a neuroblastom (N2a-NB) cells[1][2].

Name	guaiazulene
Synonym	More Synonyms

Description	Guaiazulene is present in several essential oils of medicinal and aromatic plants, with antioxidant activity. Guaiazulene has in vitro cytotoxic activity against neuron and N2a neuroblastom (N2a-NB) cells[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kourounakis AP, et al. Antioxidant activity of guaiazulene and protection against paracetamol hepatotoxicity in rats. J Pharm Pharmacol. 1997 Sep;49(9):938-42. [2]. Togar B, et al. Guaiazulene biochemical activity and cytotoxic and genotoxic effects on rat neuron and N2a neuroblastom cells. J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):29-33.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Kourounakis AP, et al. Antioxidant activity of guaiazulene and protection against paracetamol hepatotoxicity in rats. J Pharm Pharmacol. 1997 Sep;49(9):938-42.

[2]. Togar B, et al. Guaiazulene biochemical activity and cytotoxic and genotoxic effects on rat neuron and N2a neuroblastom cells. J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):29-33.

Density	0.976
Boiling Point	305.4±22.0 °C at 760 mmHg
Melting Point	27-29 °C(lit.)
Molecular Formula	C₁₅H₁₈
Molecular Weight	198.303
Flash Point	142.3±13.1 °C
Exact Mass	198.140854
LogP	5.71
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.573
InChIKey	FWKQNCXZGNBPFD-UHFFFAOYSA-N
SMILES	Cc1ccc(C(C)C)cc2c(C)ccc1-2
Storage condition	2-8°C

guaiazulene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CO4790000

CHEMICAL NAME :: Azulene, 1,4-dimethyl-7-isopropyl-

CAS REGISTRY NUMBER :: 489-84-9

BEILSTEIN REFERENCE NO. :: 1365001

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H18

MOLECULAR WEIGHT :: 198.33

WISWESSER LINE NOTATION :: L57J B1 F1 IY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,615,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1220 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 54,362,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 525 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 54,362,1958

Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S36/37/39-S26-S22
WGK Germany	3
RTECS	CO4790000

Precursor 0
DownStream 7
CAS#:624-49-7 Dimethyl fumarate CAS#:624-48-6 dimethyl maleate CAS#:6223-35-4 sodium gualenate CAS#:16915-32-5 3,8-dimethyl-5-...
CAS#:64-18-6 Formic Acid CAS#:64-19-7 acetic acid CAS#:67-64-1 Acetone

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: Antiretroviral activity against HIV-1 based virus like particles infected in U2OS cel...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL3773509

Name: Cytotoxicity against human U2OS cells assessed as cell viability at highest non-toxic...
Source: ChEMBL
Target: U2OS
External Id: CHEMBL3773508

Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Total 359, Current Page 1 of 36

1,4-Dimethyl-7-(propan-2-yl)azulen

Guajazulene

1,4-dimethyl-7-propan-2-ylazulene

Cuteazul

Gurjunazulen

Eucazulen

Vetivazulen

Azulon

Vaumigan

EINECS 207-701-2

MFCD00003811

7-Isopropyl-1,4-dimethylazulene

guaiazulene

1,4-Dimethyl-7-isopropylazulene (JAN)

1,4-Dimethyl-7-isopropylazulene

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: guaiazulene
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Guaiazulene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: guaiazulene
Price: ￥1208.0/25g ￥548.0/5g
Purity: 99.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

naturewill
China
Product Name: guaiazulene
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFUCHEM--High purity 489-84-9 Guaiazulene
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

guaiazulene suppliers

Price: ￥350/1 mg

Reference only. check more guaiazulene price

guaiazulene

Use of guaiazulene

Names

guaiazulene Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Precursor & DownStream

guaiazuleneBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.