Glycine-d2
Glycine-d2 structure
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Common Name | Glycine-d2 | ||
|---|---|---|---|---|
| CAS Number | 4896-75-7 | Molecular Weight | 77.079 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 240.9±23.0 °C at 760 mmHg | |
| Molecular Formula | C2H3D2NO2 | Melting Point | 240ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 99.5±22.6 °C | |
Use of Glycine-d2Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-amino-2,2-dideuterioacetic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 240.9±23.0 °C at 760 mmHg |
| Melting Point | 240ºC (dec.)(lit.) |
| Molecular Formula | C2H3D2NO2 |
| Molecular Weight | 77.079 |
| Flash Point | 99.5±22.6 °C |
| Exact Mass | 77.044579 |
| PSA | 63.32000 |
| LogP | -1.03 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.461 |
| InChIKey | DHMQDGOQFOQNFH-DICFDUPASA-N |
| SMILES | NCC(=O)O |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| RIDADR | NONH for all modes of transport |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~97%
Glycine-d2 CAS#:4896-75-7 |
| Literature: Mitulovi, Goran; Laemmerhofer, Michael; Maier; Lindner, Wolfgang Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 5 p. 449 - 461 |
|
~%
Glycine-d2 CAS#:4896-75-7 |
| Literature: Hellerstein, Marc K. Patent: US2003/228259 A1, 2003 ; Location in patent: Page 4 ; |
|
~%
Glycine-d2 CAS#:4896-75-7 |
| Literature: Hellerstein, Marc K. Patent: US2003/228259 A1, 2003 ; Location in patent: Page 4 ; |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
|---|---|
| DownStream 3 | |
CAS#:284665-11-8
CAS#:85047-08-1
CAS#:42492-65-9This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2,2-2H2>glycine-2,2-d2 |
| Glycine-2,2-d2 |
| <2-2H2>glycine |
| (2,2-H)Glycine |
| MFCD00075077 |
| Glycine-d2 |
| Glycine-2,2-d |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of 2-amino-2,2-dideuterioacetic acid? |
| A: Main uses of 2-amino-2,2-dideuterioacetic acid: Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. |
| Q: What is the boiling point of 2-amino-2,2-dideuterioacetic acid? |
| A: Boiling point of 2-amino-2,2-dideuterioacetic acid is 240.9±23.0 °C at 760 mmHg. |
| Q: What is the InChIKey of 2-amino-2,2-dideuterioacetic acid? |
| A: InChIKey of 2-amino-2,2-dideuterioacetic acid is DHMQDGOQFOQNFH-DICFDUPASA-N. |
| Q: What is the LogP of 2-amino-2,2-dideuterioacetic acid? |
| A: LogP of 2-amino-2,2-dideuterioacetic acid is -1.03. |
| Q: What is the molecular weight of 2-amino-2,2-dideuterioacetic acid? |
| A: Molecular weight of 2-amino-2,2-dideuterioacetic acid is 77.079. |
| Q: What are the upstream materials of 2-amino-2,2-dideuterioacetic acid? |
| A: Related upstream materials(CAS) of 2-amino-2,2-dideuterioacetic acid: 56-40-6;298-12-4. |
| Q: What is the polar surface area (PSA) of 2-amino-2,2-dideuterioacetic acid? |
| A: Polar surface area (PSA) of 2-amino-2,2-dideuterioacetic acid is 63.32000. |
| Q: What English synonyms does 2-amino-2,2-dideuterioacetic acid have? |
| A: English synonyms of 2-amino-2,2-dideuterioacetic acid: 2,2-2H2>glycine-2,2-d2, Glycine-2,2-d2, glycine, (2,2-H)Glycine, MFCD00075077, Glycine-d2, Glycine-2,2-d. |
| Q: What is the SMILES notation of 2-amino-2,2-dideuterioacetic acid? |
| A: SMILES notation of 2-amino-2,2-dideuterioacetic acid is NCC(=O)O. |
| Q: What is the melting point of 2-amino-2,2-dideuterioacetic acid? |
| A: Melting point of 2-amino-2,2-dideuterioacetic acid is 240ºC (dec.)(lit.). |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |