Mesaconic acid

Modify Date: 2025-08-25 11:01:52

Mesaconic acid structure	Common Name	Mesaconic acid
	CAS Number	498-24-8	Molecular Weight	130.09900
	Density	1.387 g/cm3	Boiling Point	336.6ºC at 760 mmHg
	Molecular Formula	C₅H₆O₄	Melting Point	200-202ºC
	MSDS	Chinese USA	Flash Point	171.5ºC
	Symbol	GHS07	Signal Word	Warning

Use of Mesaconic acid

Mesaconic acid is used as a fire retardant, as recent studies revealed this acid is a competitive inhibitor of fumarate reduction.

Name	mesaconic acid
Synonym	More Synonyms

Density	1.387 g/cm3
Boiling Point	336.6ºC at 760 mmHg
Melting Point	200-202ºC
Molecular Formula	C₅H₆O₄
Molecular Weight	130.09900
Flash Point	171.5ºC
Exact Mass	130.02700
PSA	74.60000
LogP	0.10190
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.514
InChIKey	HNEGQIOMVPPMNR-NSCUHMNNSA-N
SMILES	CC(=CC(=O)O)C(=O)O
Storage condition	2-8°C

Mesaconic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OX5075000

CHEMICAL NAME :: Mesaconic acid

CAS REGISTRY NUMBER :: 498-24-8

BEILSTEIN REFERENCE NO. :: 1722680

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H6-O4

MOLECULAR WEIGHT :: 130.11

WISWESSER LINE NOTATION :: QVY1&U1VQ -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,147,1954

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	OX5075000
HS Code	2917190090

Precursor 10
CAS#:97-65-4 Itaconic acid CAS#:498-23-7 Citraconic acid CAS#:2409-52-1 Itaconic acid d... CAS#:6061-13-8 (2S,3S)-2-AMINO...
CAS#:616-02-4 Citraconic anhydride CAS#:609-14-3 Ethyl 2-methyla... CAS#:553-97-9 2-Methylcyclohe... CAS#:112365-92-1 (2S,3S)-[3-2H]-...
CAS#:88-20-0 2-Toluenesulfon... CAS#:7298-96-6 D,L-threo-β-met...
DownStream 10
CAS#:3641-51-8 (R)-(+)-Methyls... CAS#:2174-58-5 (2S)-2-methylbu... CAS#:79-41-4 Methacrylic acid CAS#:498-23-7 Citraconic acid
CAS#:97-65-4 Itaconic acid CAS#:498-89-5 tetrahydro-5-ox... CAS#:594-61-6 2-Hydroxyisobut... CAS#:187737-37-7 propene
CAS#:17498-50-9 L-Valine hydroc... CAS#:20537-97-7 2-methylbut-2-e...

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes.

J. Pharmacol. Exp. Ther. 352(1) , 90-7, (2015)

Monomethylfumarate (MMF) is thought to be the bioactive ingredient of the drug Fumaderm (Biogen Idec, Cambridge, MA), licensed in Germany since 1994 for the treatment of moderate-to-severe psoriasis. ...

In vitro pharmacokinetics of anti-psoriatic fumaric acid esters.

BMC Pharmacol. 4 , 22, (2004)

Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist o...

The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist.

Biochem. Biophys. Res. Commun. 375(4) , 562-5, (2008)

Nicotinic acid has been used for several decades to treat dyslipidemia. In mice, the lipid-lowing effect of nicotinic acid is mediated by the Gi coupled receptor PUMA-G. In humans, high (GPR109A) and ...

Methylfumaric Acid

EINECS 207-859-2

Mesaconic Acid

MFCD00002653

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Mesaconic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Mesaconic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Mesaconic acid
Price: ￥1018.0/10g ￥2038.0/25g ￥5418.0/100g
Purity: 97.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

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Price: ￥4563/100g

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Mesaconic acid

Use of Mesaconic acid

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MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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