Rhododendrol
Modify Date: 2024-01-02 12:20:26
Rhododendrol structure
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Common Name | Rhododendrol | ||
|---|---|---|---|---|
| CAS Number | 501-96-2 | Molecular Weight | 166.22 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 315.4±17.0 °C at 760 mmHg | |
| Molecular Formula | C10H14O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 153.4±15.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of RhododendrolRhododendrol can induce leukoderma. Rhododendrol induces generation of hydroxyl radicals and melanocyte cytotoxicity by increasing glutathione levels. Rhododendrol is a phenolic compound that can be isolated from plants such as Acer nikoense and Betula platyphylla[1]. |
| Name | 4-[(3R)-3-Hydroxybutyl]phenol |
|---|---|
| Synonym | More Synonyms |
| Description | Rhododendrol can induce leukoderma. Rhododendrol induces generation of hydroxyl radicals and melanocyte cytotoxicity by increasing glutathione levels. Rhododendrol is a phenolic compound that can be isolated from plants such as Acer nikoense and Betula platyphylla[1]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 315.4±17.0 °C at 760 mmHg |
| Molecular Formula | C10H14O2 |
| Molecular Weight | 166.22 |
| Flash Point | 153.4±15.5 °C |
| Exact Mass | 166.099380 |
| PSA | 40.46000 |
| LogP | 1.49 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.552 |
| Storage condition | ?20°C |
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T-Cell Responses to Tyrosinase-Derived Self-Peptides in Patients with Leukoderma Induced by Rhododendrol: Implications for Immunotherapy Targeting Melanoma.
Dermatology 232 , 44-9, (2016) Rhododendrol, a phenolic compound contained in lightening/whitening cosmetics, can bind and inhibit tyrosinase and was reported to induce leukoderma in Japan. Only 2% of the cosmetics users are affect... |
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Rhododendrol, a depigmentation-inducing phenolic compound, exerts melanocyte cytotoxicity via a tyrosinase-dependent mechanism.
Pigment Cell Melanoma Res. 27(5) , 754-63, (2014) Rhododendrol, an inhibitor of melanin synthesis developed for lightening/whitening cosmetics, was recently reported to induce a depigmentary disorder principally at the sites of repeated chemical cont... |
| 4-[(3R)-3-Hydroxybutyl]phenol |
| Benzenepropanol, 4-hydroxy-α-methyl- |
| 4-(3-Hydroxybutyl)phenol |
| 4-(p-Hydroxyphenyl)-2-butanol |
| Benzenepropanol, 4-hydroxy-α-methyl-, (R)- |
| Benzenepropanol, 4-hydroxy-α-methyl-, (αR)- |
| 2-Butanol, 4-(p-hydroxyphenyl)- |
| UNII:12QWN45UL0 |
| Rhododendrol |
| (-)-Rhododendrol |