Soyasapogenol A

Modify Date: 2025-08-27 15:50:47

Soyasapogenol A structure	Common Name	Soyasapogenol A
	CAS Number	508-01-0	Molecular Weight	474.71600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₅₀O₄	Melting Point	308-312 °C
	MSDS	N/A	Flash Point	N/A

Use of Soyasapogenol A

Soyasapogenol A, a triterpene compound, isolated from the roots of Abrus cantoniensis. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model[1][2].

Name	Soyasapogenol A
Synonym	More Synonyms

Description	Soyasapogenol A, a triterpene compound, isolated from the roots of Abrus cantoniensis. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Inflammation/Immunology
References	[1]. Chiang TC, et al. Isolation and structural elucidation of some sapogenols from Abrus cantoniensis. Planta Med. 1982 Sep;46(1):52-5. [2]. Kuzuhara H, et al. Protective effects of soyasapogenol A on liver injury mediated by immune response in a concanavalin A-induced hepatitis model. Eur J Pharmacol. 2000 Mar 10;391(1-2):175-81.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Inflammation/Immunology

References

[1]. Chiang TC, et al. Isolation and structural elucidation of some sapogenols from Abrus cantoniensis. Planta Med. 1982 Sep;46(1):52-5.

[2]. Kuzuhara H, et al. Protective effects of soyasapogenol A on liver injury mediated by immune response in a concanavalin A-induced hepatitis model. Eur J Pharmacol. 2000 Mar 10;391(1-2):175-81.

Melting Point	308-312 °C
Molecular Formula	C₃₀H₅₀O₄
Molecular Weight	474.71600
Exact Mass	474.37100
PSA	80.92000
LogP	5.08290
InChIKey	CDDWAYFUFNQLRZ-KJVHGCRFSA-N
SMILES	CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(CO)C5CCC4(C)C3(C)CCC2(C)C(O)C1O

Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL1763601

Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL1763602

Name: Cytotoxicity against mouse RAW264.7 cells at 25 to 200 ug/ml after 24 hrs by MTT assa...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL1763507

Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL1763603

Name: Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW264.7 ...
Source: ChEMBL
Target: Nitric oxide synthase, inducible
External Id: CHEMBL1763605

Name: Hepatoprotective activity against aflatoxin B1 (10e-5 M) induced Hep G2 cells at a do...
Source: ChEMBL
Target: HepG2
External Id: CHEMBL693614

Name: Inhibition of iNOS activity in LPS-stimulated mouse RAW264.7 cells assessed as conver...
Source: ChEMBL
Target: Nitric oxide synthase, inducible
External Id: CHEMBL1763593

Name: Inhibition of iNOS activity in LPS-stimulated mouse RAW264.7 cells assessed as conver...
Source: ChEMBL
Target: Nitric oxide synthase, inducible
External Id: CHEMBL1763594

Name: Inhibition of iNOS activity in LPS-stimulated mouse RAW264.7 cells assessed as conver...
Source: ChEMBL
Target: Nitric oxide synthase, inducible
External Id: CHEMBL1763595

Name: Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of HMGB...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL5055017

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.