Mitraphylline

Modify Date: 2025-08-25 09:40:53

Mitraphylline Structure
Mitraphylline structure
Common Name Mitraphylline
CAS Number 509-80-8 Molecular Weight 368.42600
Density 1.33 g/cm3 Boiling Point 555.2ºC
Molecular Formula C21H24N2O4 Melting Point 258-267 °C
MSDS N/A Flash Point 289.6ºC

 Use of Mitraphylline


Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].

 Names

Name methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
Synonym More Synonyms

 Mitraphylline Biological Activity

Description Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].
Related Catalog
References

[1]. Montserrat-de la Paz S, et al. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils. Phytomedicine. 2016 Feb 15;23(2):141-8.

 Chemical & Physical Properties

Density 1.33 g/cm3
Boiling Point 555.2ºC
Melting Point 258-267 °C
Molecular Formula C21H24N2O4
Molecular Weight 368.42600
Flash Point 289.6ºC
Exact Mass 368.17400
PSA 67.87000
LogP 2.13840
Index of Refraction 1.635

 Synonyms

ajmalicine oxindole-B
HMS2267P09
Mitraphilline
EINECS 208-106-0
rubradinine
Mitraphylline
Mitraphyllin
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