yamogenin

Modify Date: 2025-09-12 20:34:54

yamogenin structure	Common Name	yamogenin
	CAS Number	512-06-1	Molecular Weight	414.621
	Density	1.1±0.1 g/cm3	Boiling Point	527.1±50.0 °C at 760 mmHg
	Molecular Formula	C₂₇H₄₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	272.6±30.1 °C

Use of yamogenin

Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes[1].

Name	Yamogenin
Synonym	More Synonyms

Description	Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> LXR Research Areas >> Metabolic Disease
Target	IC50: TG accumulation; liver X receptor (LXR)[1]
References	[1]. Moriwaki S, et al. Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes.Biosci Biotechnol Biochem. 2014;78(7):1231-6.

Density	1.1±0.1 g/cm3
Boiling Point	527.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₇H₄₂O₃
Molecular Weight	414.621
Flash Point	272.6±30.1 °C
Exact Mass	414.313385
PSA	38.69000
LogP	5.84
Vapour Pressure	0.0±3.1 mmHg at 25°C
Index of Refraction	1.564
Storage condition	-20℃