LIGHT GREEN SF YELLOWISH

Modify Date: 2024-01-08 18:54:02

LIGHT GREEN SF YELLOWISH Structure
LIGHT GREEN SF YELLOWISH structure
Common Name LIGHT GREEN SF YELLOWISH
CAS Number 5141-20-8 Molecular Weight 792.848
Density N/A Boiling Point N/A
Molecular Formula C37H34N2Na2O9S3 Melting Point 290ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A

 Use of LIGHT GREEN SF YELLOWISH


Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains[1][2].

 Names

Name acid green 5
Synonym More Synonyms

 LIGHT GREEN SF YELLOWISH Biological Activity

Description Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains[1][2].
Related Catalog

 Chemical & Physical Properties

Melting Point 290ºC (dec.)(lit.)
Molecular Formula C37H34N2Na2O9S3
Molecular Weight 792.848
Exact Mass 792.122192
PSA 202.99000
LogP 8.26930
Storage condition Store at RT.
Water Solubility H2O: soluble1mg/mL

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BQ4900000
CHEMICAL NAME :
Ammonium, ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(p-sulfo phenyl)benzylidene)- 2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-, hydroxide, inner salt, disodium salt
CAS REGISTRY NUMBER :
5141-20-8
LAST UPDATED :
199701
DATA ITEMS CITED :
19
MOLECULAR FORMULA :
C37-H36-N2-O9-S3.2Na
MOLECULAR WEIGHT :
794.91
WISWESSER LINE NOTATION :
L6Y DYJ AUYR DSWQ&R DN2&1R CSWQ&& DUK2&1R CSWQ &Q &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
525 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1369 gm/kg/1Y-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
682 gm/kg/65W-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1300 gm/kg/86W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6825 mg/kg/46W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
819 gm/kg
SEX/DURATION :
male 65 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
553 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 189,223,1987 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,209,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,209,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1357 No. of Facilities: 766 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 2347 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1357 No. of Facilities: 1886 (estimated) No. of Industries: 16 No. of Occupations: 27 No. of Employees: 18350 (estimated) No. of Female Employees: 7859 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases 68
Safety Phrases 36/37
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS BQ4900000

 Articles7

More Articles
Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)

Short-term in vivo evaluation of novel vital dyes for intraocular surgery.

Retina (Philadelphia, Pa.) 26(6) , 673-8, (2006)

To evaluate the staining characteristics and safety of potential new dyes for intraocular surgery in porcine eyes.Four dyes in different solutions (light green SF yellowish [LGSF]: 2%; copper(II) phth...

Administration of novel dyes for intraocular surgery: an in vivo toxicity animal study.

Invest. Ophthalmol. Vis. Sci. 47(8) , 3573-8, (2006)

To investigate the effect of intravitreal injections of new vital dyes on the retina, the retinal pigment epithelium (RPE) and the choroid in an in vivo rat model.Rats were injected intravitreally wit...

 Synonyms

DC Green No.5
benzenemethanaminium, N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, sodium salt (1:2)
Disodium 3-[(ethyl{(1Z,4Z)-4-[{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}(4-sulfonatophenyl)methylene]-2,5-cyclohexadien-1-ylidene}ammonio)methyl]benzenesulfonate
MFCD00012121
Light green
Ethyl[4-[p-[ethyl(m-sulfobenzyl)amino]-a-(p-sulfophenyl)benzylidene]-2,5-cyclohexadien-1-ylidene](m-sulfobenzyl)ammonium Hydroxide Inner Salt Disodium Salt
Light Green SF,Yellowish,high purity biological stain
foodgreen2
Disodium 3-[(ethyl{(1E,4E)-4-[{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}(4-sulfonatophenyl)methylene]-2,5-cyclohexadien-1-ylidene}ammonio)methyl]benzenesulfonate
ACID GREEN
c.i.670
Acid Green 5
Disodium 3-[(ethyl{(1E,4E)-4-[{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}(4-sulfonatophenyl)methylene]cyclohexa-2,5-dien-1-ylidene}ammonio)methyl]benzenesulfonate
Light Green SF Yellowish
light green SF,yellowish
C.I. Acid Green 5
Benzenemethanaminium, N-ethyl-N-[(1E,4E)-4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, sodium salt (1:2)
benzenemethanaminium, N-ethyl-N-[(1Z,4Z)-4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, sodium salt (1:2)
Green SF
EINECS 225-906-5
my/68
N-Ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfobenzenemethanaminium Hydroxide Inner Salt Disodium Salt
FD & C Green No.2
Lissamine Green SF
Light Green SF Yellowish (Formerly Food Green No.2) [as an Indicator
lichtgruen
MIDORI205
Disodium 3-[(ethyl{4-[{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}(4-sulfonatophenyl)methylene]cyclohexa-2,5-dien-1-ylidene}ammonio)methyl]benzenesulfonate
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