Esflurbiprofen

Modify Date: 2024-01-02 19:53:52

Use of Esflurbiprofen

(S)-Flurbiprofen is an active enantiomer of Flurbiprofen, with IC50 values of 0.48 μM and 0.47 μM for COX-1 and COX-2, respectively[1].

Name	(S)-flurbiprofen
Synonym	More Synonyms

Description	(S)-Flurbiprofen is an active enantiomer of Flurbiprofen, with IC50 values of 0.48 μM and 0.47 μM for COX-1 and COX-2, respectively[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX Signaling Pathways >> Immunology/Inflammation >> PGE synthase
Target	COX-1:0.48 μM (IC50) COX-2:0.47 μM (IC50)
In Vitro	(S)-Flurbiprofen (10–7 M) results in a total suppression of basal and stimulated PGE2 release in rat skin[2].
References	[1]. A Carabaza, et al. Stereoselective Inhibition of Inducible Cyclooxygenase by Chiral Nonsteroidal Antiinflammatory Drugs. J Clin Pharmacol. 1996 Jun;36(6):505-12. [2]. B Averbeck, et al. Inflammatory Mediators Do Not Stimulate CGRP Release if Prostaglandin Synthesis Is Blocked by S(+)-flurbiprofen in Isolated Rat Skin. Inflamm Res. 2003 Dec;52(12):519-23.

[1,1'-biphenyl]-4-acetic acid, 2-fluoro-a-methyl-

2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid

2-FLUORO-α-METHYL-4-BIPHENYLACETIC ACID

2-(2-Fluoro-4-biphenylyl)propanoic acid

Froben

Anside

EINECS 257-263-1

d-Flurbiprofen

[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-

Stayban

Esflurbiprofen

MFCD00866152

(S)-Flurbiprofen

2-(2-fluorobiphenyl-4-yl)propanoic acid

Ocufen

Ansaid

(±)-Flurbiprofen

2-(2-fluoro-4-biphenylyl)propionic acid

Zepolas

Adfeed

rac-Flurbiprofen

tarenflurbil

Flurbiprofen

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Price: ￥750/100 mg

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