1-Benzyl-3-pyrrolidinone

Modify Date: 2026-07-01 19:43:50

1-Benzyl-3-pyrrolidinone structure	Common Name	1-Benzyl-3-pyrrolidinone
	CAS Number	5291-77-0	Molecular Weight	175.227
	Density	1.1±0.1 g/cm3	Boiling Point	343.0±21.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₁₃NO	Melting Point	154 - 156ºC
	MSDS	Chinese USA	Flash Point	141.3±12.6 °C
	Symbol	GHS07	Signal Word	Warning

Summary: 1-Benzyl-2-pyrrolidinone, also known as N-benzylpyrrolidone, has a molecular formula of C11H13NO and a molecular weight of 175.227. It appears as a transparent, colorless to yellow liquid with a melting point of 154-156°C and a boiling point of 343.0±21.0°C. The density is 1.1±0.1 g/cm³. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	1-Benzyl-2-pyrrolidinone
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.1±0.1 g/cm3
Boiling Point	343.0±21.0 °C at 760 mmHg
Melting Point	154 - 156ºC
Molecular Formula	C₁₁H₁₃NO
Molecular Weight	175.227
Flash Point	141.3±12.6 °C
Exact Mass	175.099716
PSA	20.31000
LogP	1.25
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.578
InChIKey	LVUQCTGSDJLWCE-UHFFFAOYSA-N
SMILES	O=C1CCCN1Cc1ccccc1

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

1-Benzyl-3-pyrrolidinone MSDS(Chinese)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2933790090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 9
CAS#:616-45-5 2-Pyrrolidinone CAS#:100-52-7 Benzaldehyde CAS#:96-48-0 gamma-Butyrolactone CAS#:100-46-9 Benzylamine
CAS#:4383-22-6 N-Allylbenzylamine CAS#:201230-82-2 carbon monoxide CAS#:78805-05-7 (E)-N-allyl-N-b... CAS#:78805-06-8 (E)-N-benzyl-3-...
CAS#:26735-10-4 4-(benzylamino)...
DownStream 10
CAS#:91-16-7 1,2-Dimethoxybenzene CAS#:107770-10-5 1-benzyl-3-(3,4... CAS#:220024-87-3 1-benzyl-2,2-di... CAS#:616-45-5 2-Pyrrolidinone
CAS#:26735-10-4 4-(benzylamino)... CAS#:2142-06-5 N-Phenylmethyl ... CAS#:2399-66-8 1-Benzoylpyrrol... CAS#:191403-66-4 (S)-1-BENZYL-4-...
CAS#:109859-99-6 1-Benzyl-2-oxo-... CAS#:29897-82-3 1-benzylpyrrolidine

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Aminoborohydrides. 11. Facile reduction of N-alkyl lactams to the corresponding amines using lithium aminoborohydrides.

Org. Lett. 1(5) , 799-801, (1999)

[reaction: see text] Various five- and six-membered N-alkyl lactams were reduced to the corresponding cyclic amines using lithium N,N-dialkylaminoborohydrides (LAB). Most of the reductions were essent...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity

Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

Name: Kinase Inhibition Assay from Article 10.1021/jm040895g: "SAR and 3D-QSAR studies on t...
Source: BindingDB
Target: N/A
External Id: BindingDB_987_1

Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN

Total 115, Current Page 1 of 12

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1-benzylpyrrolidin-2-one

1-Benzyl-3-pyrrolidinone

N-benzyl-3-pyrrolidinone

MFCD00003195

1-benzylpyrrolidin-3-one

1-Benzyl-2-pyrrolidinone

N-Benzylpyrrolidin-2-one

EINECS 226-131-5

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of 1-Benzyl-2-pyrrolidinone?

A: CAS number of 1-Benzyl-2-pyrrolidinone is 5291-77-0.

Q: What is the polar surface area (PSA) of 1-Benzyl-2-pyrrolidinone?

A: Polar surface area (PSA) of 1-Benzyl-2-pyrrolidinone is 20.31000.

Q: What is the LogP of 1-Benzyl-2-pyrrolidinone?

A: LogP of 1-Benzyl-2-pyrrolidinone is 1.25.

Q: What English synonyms does 1-Benzyl-2-pyrrolidinone have?

A: English synonyms of 1-Benzyl-2-pyrrolidinone: 1-benzylpyrrolidin-2-one, 1-Benzyl-3-pyrrolidinone, N-benzyl-3-pyrrolidinone, MFCD00003195, 1-benzylpyrrolidin-3-one, 1-Benzyl-2-pyrrolidinone, N-Benzylpyrrolidin-2-one, EINECS 226-131-5.

Q: What are the downstream products of 1-Benzyl-2-pyrrolidinone?

A: Related downstream products(CAS) of 1-Benzyl-2-pyrrolidinone: 91-16-7;107770-10-5;220024-87-3;616-45-5;26735-10-4;2142-06-5;2399-66-8;191403-66-4;109859-99-6;29897-82-3.

Q: What is the melting point of 1-Benzyl-2-pyrrolidinone?

A: Melting point of 1-Benzyl-2-pyrrolidinone is 154 - 156ºC.

Q: What is the InChIKey of 1-Benzyl-2-pyrrolidinone?

A: InChIKey of 1-Benzyl-2-pyrrolidinone is LVUQCTGSDJLWCE-UHFFFAOYSA-N.

Q: What is the molecular weight of 1-Benzyl-2-pyrrolidinone?

A: Molecular weight of 1-Benzyl-2-pyrrolidinone is 175.227.

Q: What is the SMILES notation of 1-Benzyl-2-pyrrolidinone?

A: SMILES notation of 1-Benzyl-2-pyrrolidinone is O=C1CCCN1Cc1ccccc1.

Q: What is the safety information for 1-Benzyl-2-pyrrolidinone?

A: Safety information for 1-Benzyl-2-pyrrolidinone: S26-S37/39.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-Benzyl-3-pyrrolidinone
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-Benzyl-2-pyrrolidinone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

1-Benzyl-3-pyrrolidinone suppliers

Price: ￥2951/1000g

Reference only. check more 1-Benzyl-3-pyrrolidinone price

1-Benzyl-3-pyrrolidinone

Names

Chemical & Physical Properties

MSDS

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles1

1-Benzyl-3-pyrrolidinoneBioassay

Synonyms

1-Benzyl-3-pyrrolidinone | FAQ

1-Benzyl-3-pyrrolidinonefactory

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.