Morellic acid

Modify Date: 2024-01-02 10:05:42

Morellic acid Structure
Morellic acid structure
Common Name Morellic acid
CAS Number 5304-71-2 Molecular Weight 453.57500
Density 1.36±0.1 g/cm3(Predicted) Boiling Point 777.6±60.0 °C(Predicted)
Molecular Formula C33H36O8 Melting Point 94 °C
MSDS N/A Flash Point N/A

 Use of Morellic acid


Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity[1].

 Names

Name 1'-benzyl-2-(4-methoxyphenyl)-9-methylspiro[1,10b-dihydropyrazolo[1,5-c][1,3]benzoxazine-5,4'-piperidine]
Synonym More Synonyms

 Morellic acid Biological Activity

Description Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity[1].
Related Catalog
Target

IC50: antiangiogenic[1]

In Vitro Morellic acid inhibits the migration of HUVEC at a low concentration of 0.5 µM in HUVEC cell migration assay in vitro[1].
References

[1]. Li SL, et al. Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin from Garcinia hanburyi.Biomed Chromatogr. 2008 Jun;22(6):637-44.

[2]. Yang J, et al.In vitro and in vivo antiangiogenic activity of caged polyprenylated xanthones isolated from Garcinia hanburyi Hook. f. Molecules. 2013 Dec 11;18(12):15305-13.

 Chemical & Physical Properties

Density 1.36±0.1 g/cm3(Predicted)
Boiling Point 777.6±60.0 °C(Predicted)
Melting Point 94 °C
Molecular Formula C33H36O8
Molecular Weight 453.57500
Exact Mass 453.24200
PSA 37.30000
LogP 4.85080

 Synonyms

1-benzyl-2'-(4-methoxyphenyl)-9'-methyl-1',10b'-dihydrospiro[piperidine-4,5'-pyrazolo[1,5-c][1,3]benzoxazine]