3-Amino-7-(methylamino)phenothiazin-5-ium chloride

Modify Date: 2024-01-22 11:57:19

3-Amino-7-(methylamino)phenothiazin-5-ium chloride structure	Common Name	3-Amino-7-(methylamino)phenothiazin-5-ium chloride
	CAS Number	531-57-7	Molecular Weight	277.77
	Density	N/A	Boiling Point	385.1ºC at 760 mmHg
	Molecular Formula	C₁₃H₁₂ClN₃S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	186.7ºC

Use of 3-Amino-7-(methylamino)phenothiazin-5-ium chloride

Azure C is the product of sequential enzymatic oxidation of Methylene blue (MB) or Azure B (AB). Azure C serves as the substrate of horseradish peroxidase (HRP)[1][2].

Name	azure C
Synonym	More Synonyms

Description	Azure C is the product of sequential enzymatic oxidation of Methylene blue (MB) or Azure B (AB). Azure C serves as the substrate of horseradish peroxidase (HRP)[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Ferreira-Leitão V S, et al. Methylene blue and azure B oxidation by horseradish peroxidase: a comparative evaluation of class II and class III peroxidases. Applied Catalysis B: Environmental, 2003, 42(2): 213-221. [2]. Lo Cascio F, et al. Azure C Targets and Modulates Toxic Tau Oligomers. ACS Chem Neurosci. 2018 Jun 20;9(6):1317-1326.

Description

Azure C is the product of sequential enzymatic oxidation of Methylene blue (MB) or Azure B (AB). Azure C serves as the substrate of horseradish peroxidase (HRP)[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Ferreira-Leitão V S, et al. Methylene blue and azure B oxidation by horseradish peroxidase: a comparative evaluation of class II and class III peroxidases. Applied Catalysis B: Environmental, 2003, 42(2): 213-221.

[2]. Lo Cascio F, et al. Azure C Targets and Modulates Toxic Tau Oligomers. ACS Chem Neurosci. 2018 Jun 20;9(6):1317-1326.

Boiling Point	385.1ºC at 760 mmHg
Molecular Formula	C₁₃H₁₂ClN₃S
Molecular Weight	277.77
Flash Point	186.7ºC
Exact Mass	277.04400
PSA	79.18000
LogP	1.01270

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP5680000

CHEMICAL NAME :: Phenothiazin-5-ium, 3-amino-7-methylamino-, chloride

CAS REGISTRY NUMBER :: 531-57-7

LAST UPDATED :: 199504

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C13-H12-N3-S.Cl

MOLECULAR WEIGHT :: 277.79

WISWESSER LINE NOTATION :: T C666 BN ISJ FZ MM1 &G &12/23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 20 umol/L/5H (Continuous)

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1536 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 36 (estimated) No. of Female Employees: 16 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SP5680000
HS Code	2934300000

methylene blue

CAS#:152071-32-4

3-Amino-7-(meth...

CAS#:531-57-7

Literature: Materials Research Bulletin, , vol. 49, # 1 p. 544 - 551

HS Code	2934300000
Summary	2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Note from the Biological Stain Commission: revision of azure B assay protocol.

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(7-aminophenothiazin-3-ylidene)-methylazanium,chloride

MFCD00067677

N-Methylthionine

EINECS 208-512-8

3-Amino-7-(methylamino)phenothiazin-5-ium chloride

Use of 3-Amino-7-(methylamino)phenothiazin-5-ium chloride

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MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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