Esculin
Esculin structure
|
Common Name | Esculin | ||
|---|---|---|---|---|
| CAS Number | 531-75-9 | Molecular Weight | 340.29 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 697.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H16O9 | Melting Point | 203 °C | |
| MSDS | USA | Flash Point | 262.8±25.0 °C | |
Use of EsculinEsculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | esculin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2]. |
|---|---|
| Related Catalog | |
| Target |
p38 MAPK |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 697.7±55.0 °C at 760 mmHg |
| Melting Point | 203 °C |
| Molecular Formula | C15H16O9 |
| Molecular Weight | 340.29 |
| Flash Point | 262.8±25.0 °C |
| PSA | 149.82000 |
| LogP | -1.52 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.689 |
| InChIKey | XHCADAYNFIFUHF-TVKJYDDYSA-N |
| SMILES | O=c1ccc2cc(OC3OC(CO)C(O)C(O)C3O)c(O)cc2o1 |
| Water Solubility | MODERATELY SOLUBLE |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | F,C,Xi |
|---|---|
| Risk Phrases | R11 |
| Safety Phrases | S26-S36/37/39-S45-S24/25 |
| RIDADR | UN 2924 3/PG 2 |
| WGK Germany | 3 |
| RTECS | DJ3085000 |
| HS Code | 2942000000 |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2942000000 |
|---|
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Crataegin |
| 7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside |
| EINECS 208-517-5 |
| Enallachrome |
| vitaminc2 |
| Esculetin 6-β-D-glucoside |
| POLYDROM |
| Bicolorin |
| Esculetin 6-O-glucoside |
| Polychrom |
| 7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside |
| BICOLOIN |
| 7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate |
| Esculin |
| 7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen-2-one |
| Polychrome |
| 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one |
| Esculetin 6-b-D-glucoside |
| 7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1) |
| Aesculin |
| MFCD00006879 |
| Esculetin-6-O-glucoside |
| 2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-, hydrate (1:1) |
| Escosyl |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of esculin? |
| A: CAS number of esculin is 531-75-9. |
| Q: What is the polar surface area (PSA) of esculin? |
| A: Polar surface area (PSA) of esculin is 149.82000. |
| Q: What are the uses of esculin? |
| A: Main uses of esculin: Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2]. |
| Q: What is the InChIKey of esculin? |
| A: InChIKey of esculin is XHCADAYNFIFUHF-TVKJYDDYSA-N. |
| Q: What is the molecular formula of esculin? |
| A: Molecular formula of esculin is C15H16O9. |
| Q: What is the melting point of esculin? |
| A: Melting point of esculin is 203 °C. |
| Q: What is the English name of esculin? |
| A: The English name of esculin is esculin. |
| Q: What is the molecular weight of esculin? |
| A: Molecular weight of esculin is 340.29. |
| Q: What is the safety information for esculin? |
| A: Safety information for esculin: S26-S36/37/39-S45-S24/25. |
| Q: What is the LogP of esculin? |
| A: LogP of esculin is -1.52. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| naturewill |
| Henan Tianfu Chemical Co., Ltd. |