Esculin

Modify Date: 2024-01-01 20:27:39

Esculin Structure
Esculin structure
 Common Name Esculin
CAS Number 531-75-9 Molecular Weight 340.29
Density 1.7±0.1 g/cm3 Boiling Point 697.7±55.0 °C at 760 mmHg
Molecular Formula C15H16O9 Melting Point 203 °C
MSDS USA Flash Point 262.8±25.0 °C

 Use of Esculin


Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2].

 Names

Name esculin
Synonym More Synonyms

 Esculin Biological Activity

Description Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2].
Related Catalog
Target

p38 MAPK

References

[1]. Knox K, et al. The Coumarin Glucoside, Esculin, Reveals Rapid Changes in Phloem-Transport Velocity in Response to Environmental Cues. Plant Physiol. 2018 Oct;178(2):795-807.

[2]. Song Y, et al. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy and induces anti-oxidative stress and anti-inflammatory effects via the MAPK pathway. Mol Med Rep. 2018 May;17(5):7395-7402.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 697.7±55.0 °C at 760 mmHg
Melting Point 203 °C
Molecular Formula C15H16O9
Molecular Weight 340.29
Flash Point 262.8±25.0 °C
PSA 149.82000
LogP -1.52
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.689
Water Solubility MODERATELY SOLUBLE

 Safety Information

Hazard Codes F,C,Xi
Risk Phrases R11
Safety Phrases S26-S36/37/39-S45-S24/25
RIDADR UN 2924 3/PG 2
WGK Germany 3
RTECS DJ3085000
HS Code 2942000000

 Customs

HS Code 2942000000

 Synonyms

Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
EINECS 208-517-5
Enallachrome
vitaminc2
Esculetin 6-β-D-glucoside
POLYDROM
Bicolorin
Esculetin 6-O-glucoside
Polychrom
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
BICOLOIN
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen-2-one
Polychrome
6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
Esculetin 6-b-D-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
Aesculin
MFCD00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-, hydrate (1:1)
Escosyl
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Related Compounds: More...
Esculin aglycon
305-01-1
Esculin aglucon
91753-33-2
Esculin sesquihydrate
66778-17-4
Chemsrc provides Esculin(CAS#:531-75-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Esculin are included as well.>> amp version: Esculin

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