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531-75-9

531-75-9 structure
531-75-9 structure
  • Name: Esculin
  • Chemical Name: esculin
  • CAS Number: 531-75-9
  • Molecular Formula: C15H16O9
  • Molecular Weight: 340.29
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-02-05 08:00:00
  • Modify Date: 2024-01-01 20:27:39
  • Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2].

Name esculin
Synonyms Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
EINECS 208-517-5
Enallachrome
vitaminc2
Esculetin 6-β-D-glucoside
POLYDROM
Bicolorin
Esculetin 6-O-glucoside
Polychrom
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
BICOLOIN
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen-2-one
Polychrome
6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
Esculetin 6-b-D-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
Aesculin
MFCD00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-, hydrate (1:1)
Escosyl
Description Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2].
Related Catalog
Target

p38 MAPK

References

[1]. Knox K, et al. The Coumarin Glucoside, Esculin, Reveals Rapid Changes in Phloem-Transport Velocity in Response to Environmental Cues. Plant Physiol. 2018 Oct;178(2):795-807.

[2]. Song Y, et al. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy and induces anti-oxidative stress and anti-inflammatory effects via the MAPK pathway. Mol Med Rep. 2018 May;17(5):7395-7402.

Density 1.7±0.1 g/cm3
Boiling Point 697.7±55.0 °C at 760 mmHg
Melting Point 203 °C
Molecular Formula C15H16O9
Molecular Weight 340.29
Flash Point 262.8±25.0 °C
PSA 149.82000
LogP -1.52
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.689
Water Solubility MODERATELY SOLUBLE
Hazard Codes F,C,Xi
Risk Phrases R11
Safety Phrases S26-S36/37/39-S45-S24/25
RIDADR UN 2924 3/PG 2
WGK Germany 3
RTECS DJ3085000
HS Code 2942000000
HS Code 2942000000