2,4-Dimethylthiazole-5-carboxylic acid

Modify Date: 2026-07-16 13:52:37

2,4-Dimethylthiazole-5-carboxylic acid Structure
2,4-Dimethylthiazole-5-carboxylic acid structure
Common Name 2,4-Dimethylthiazole-5-carboxylic acid
CAS Number 53137-27-2 Molecular Weight 157.190
Density 1.3±0.1 g/cm3 Boiling Point 306.2±22.0 °C at 760 mmHg
Molecular Formula C6H7NO2S Melting Point 235 °C (dec.)
MSDS Chinese USA Flash Point 139.0±22.3 °C

 Names

Name 2,4-Dimethylthiazole-5-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 306.2±22.0 °C at 760 mmHg
Melting Point 235 °C (dec.)
Molecular Formula C6H7NO2S
Molecular Weight 157.190
Flash Point 139.0±22.3 °C
Exact Mass 157.019745
PSA 78.43000
LogP 1.24
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.585
InChIKey MQGBARXPCXAFRZ-UHFFFAOYSA-N
SMILES Cc1nc(C)c(C(=O)O)s1

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2934100090

 Synthetic Route

~%

2,4-Dimethylthiazole-5-carboxylic acid Structure

2,4-Dimethylthi...

CAS#:53137-27-2

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Literature: Justus Liebigs Annalen der Chemie, , vol. 259, p. 266

~%

2,4-Dimethylthiazole-5-carboxylic acid Structure

2,4-Dimethylthi...

CAS#:53137-27-2

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Literature: Zhurnal Obshchei Khimii, , vol. 26, p. 66; engl. Ausg. S. 65

~%

2,4-Dimethylthiazole-5-carboxylic acid Structure

2,4-Dimethylthi...

CAS#:53137-27-2

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Literature: Proceedings - Indian Academy of Sciences, Section A, , # 22 p. 362,376

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 2,4-Dimethylthiazole-5-carboxylic acidBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

2,4-Dimethyl-1,3-thiazole-5-carboxylic acid
MFCD00052943
2,4-Dimethylthiazole-5-carboxylic acid
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