N-alpha-Naphthylphthalimide

Modify Date: 2026-07-22 16:35:43

N-alpha-Naphthylphthalimide Structure
N-alpha-Naphthylphthalimide structure
Common Name N-alpha-Naphthylphthalimide
CAS Number 5333-99-3 Molecular Weight 273.28500
Density 1.36g/cm3 Boiling Point 482.8ºC at 760mmHg
Molecular Formula C18H11NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 2-naphthalen-1-ylisoindole-1,3-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.36g/cm3
Boiling Point 482.8ºC at 760mmHg
Molecular Formula C18H11NO2
Molecular Weight 273.28500
Exact Mass 273.07900
PSA 37.38000
LogP 3.70540
Index of Refraction 1.726
InChIKey LPCGITYWEFRRFS-UHFFFAOYSA-N
SMILES O=C1c2ccccc2C(=O)N1c1cccc2ccccc12

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI5623000
CHEMICAL NAME :
Phthalimide, N-1-naphthyl-
CAS REGISTRY NUMBER :
5333-99-3
BEILSTEIN REFERENCE NO. :
0226898
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H11-N-O2
MOLECULAR WEIGHT :
273.30
WISWESSER LINE NOTATION :
T56 BVNVJ C- BL66J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,23,1953

 Safety Information

HS Code 2925190090

 Synthetic Route

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 N-alpha-NaphthylphthalimideBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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 Synonyms

1-naphthalen-2-yl-isoindole-1,3-dione
N-1-Naphthylphthalimide
1-naphthalen-2-yl-1H-isoindole-1,3(2H)-dione
Caswell No. 593
1-(N-phthalimido)naphthalene
1H-Isoindole-1,3(2H)-dione,2-(1-naphthalenyl)
N-naphthalen-1-yl-phthalimide
2-(naphthalen-1-yl)isoindoline-1,3-dione
2-Naphthalen-1-yl-isoindole-1,3-dione
Phthalimide,N-1-naphthyl
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