NSC 204421

Modify Date: 2024-01-02 15:54:54

NSC 204421 Structure
NSC 204421 structure
Common Name NSC 204421
CAS Number 132-66-1 Molecular Weight 291.30
Density 1.355g/cm3 Boiling Point 450.8ºC at 760mmHg
Molecular Formula C18H13NO3 Melting Point 185-190 °C
MSDS Chinese USA Flash Point 226.4ºC

 Use of NSC 204421


N-1-Naphthylphthalamic acid is a polar auxin transport inhibitor. N-1-Naphthylphthalamic acid disrupts leaf initiation, KNOX protein regulation, and formation of leaf margins in maize[1].

 Names

Name naptalam
Synonym More Synonyms

 NSC 204421 Biological Activity

Description N-1-Naphthylphthalamic acid is a polar auxin transport inhibitor. N-1-Naphthylphthalamic acid disrupts leaf initiation, KNOX protein regulation, and formation of leaf margins in maize[1].
Related Catalog
References

[1]. Ihsan BurakCam, et al. Physical and chemical properties of cow cockle seeds (Vaccaria hispanica (Mill.) Rauschert) genetic resources of Turkey.

 Chemical & Physical Properties

Density 1.355g/cm3
Boiling Point 450.8ºC at 760mmHg
Melting Point 185-190 °C
Molecular Formula C18H13NO3
Molecular Weight 291.30
Flash Point 226.4ºC
Exact Mass 291.09000
PSA 66.40000
LogP 3.86330
Vapour Pressure 6.51E-09mmHg at 25°C
Stability Stable. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TH7350000
CHEMICAL NAME :
Phthalamic acid, N-1-naphthyl-
CAS REGISTRY NUMBER :
132-66-1
BEILSTEIN REFERENCE NO. :
2814102
LAST UPDATED :
199706
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H13-N-O3
MOLECULAR WEIGHT :
291.32
WISWESSER LINE NOTATION :
L66J BMVR BVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C215,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2070 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,613,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,613,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

Hazard Statements H412
Precautionary Statements P273
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
RTECS TH7350000
HS Code 2924299090

 Synthetic Route

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NSC 204421 Structure

NSC 204421

CAS#:132-66-1

Literature: Chemische Berichte, , vol. 44, p. 1962

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NSC 204421 Structure

NSC 204421

CAS#:132-66-1

Literature: Journal of Agricultural and Food Chemistry, , vol. 43, # 9 p. 2493 - 2496

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NSC 204421 Structure

NSC 204421

CAS#:132-66-1

Literature: Journal of the American Chemical Society, , vol. 30, p. 1889

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles27

More Articles
Non-invasive quantification of endogenous root auxin transport using an integrated flux microsensor technique.

Plant J. 63(6) , 1004-16, (2010)

Indole-3-acetic acid (IAA) is a primary phytohormone that regulates multiple aspects of plant development. Because polar transport of IAA is an essential determinant of organogenesis and dynamic tropi...

Auxin modulates the enhanced development of root hairs in Arabidopsis thaliana (L.) Heynh. under elevated CO(2).

Plant Cell Environ. 34(8) , 1304-17, (2011)

Root hairs may play a critical role in nutrient acquisition of plants grown under elevated CO(2) . This study investigated how elevated CO(2) enhanced the development of root hairs in Arabidopsis thal...

Expression profile of PIN, AUX/LAX and PGP auxin transporter gene families in Sorghum bicolor under phytohormone and abiotic stress.

FEBS J. 277 , 2954-2969, (2010)

Auxin is transported by the influx carriers auxin resistant 1/like aux1 (AUX/LAX), and the efflux carriers pin-formed (PIN) and P-glycoprotein (PGP), which play a major role in polar auxin transport. ...

 Synonyms

alanap
2-(naphthalen-1-ylcarbamoyl)benzoic acid
2-(1-Naphthylcarbamoyl)benzoic acid
NAPTRO
acp322
dyanap
solo
alanape
N-(1-Naphthyl)phthalamic Acid
MFCD00037725
N-1-naphthylphthalamic acid
cyanap
2-[(1-naphthalenylamino)carbonyl]benzoic acid
alanap1
2-[(1-naphthylamino)carbonyl]benzoic acid
N-(1-Naphthyl)phthalamidic acid
NAPTALAM
6q8
2-<(1-naphthalenylamino)carbonyl>benzoic acid
NPA
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