5'-Iodoresiniferatoxin
Modify Date: 2024-01-06 19:07:35
5'-Iodoresiniferatoxin structure
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Common Name | 5'-Iodoresiniferatoxin | ||
|---|---|---|---|---|
| CAS Number | 535974-91-5 | Molecular Weight | 754.60 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 782.4±60.0 °C at 760 mmHg | |
| Molecular Formula | C37H39IO9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 427.0±32.9 °C | |
Use of 5'-Iodoresiniferatoxin5-Iodoresiniferatoxin (I-RTX) is a selective TRPV1 antagonist, with an IC50s of 0.7 and 5.4 nM for rat and human receptors, respectively. 5-Iodoresiniferatoxin induces TRPV1-dependent hypothermia in vivo[1]. |
| Name | i-rtx |
|---|---|
| Synonym | More Synonyms |
| Description | 5-Iodoresiniferatoxin (I-RTX) is a selective TRPV1 antagonist, with an IC50s of 0.7 and 5.4 nM for rat and human receptors, respectively. 5-Iodoresiniferatoxin induces TRPV1-dependent hypothermia in vivo[1]. |
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| Related Catalog | |
| Target |
rTRPV1:0.7 nM (IC50) hTRPV1:5.4 nM (IC50) |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 782.4±60.0 °C at 760 mmHg |
| Molecular Formula | C37H39IO9 |
| Molecular Weight | 754.60 |
| Flash Point | 427.0±32.9 °C |
| Exact Mass | 754.163879 |
| PSA | 120.75000 |
| LogP | 6.65 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.671 |
| [(1R,2R,6R,10S,11R,15R,17R)-13-Benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5-oxo-12,14,18-trioxapentacyclo[11.4.1.0.0.0]octadeca-3,8-dien-8-yl]methyl (4-hydroxy-3-iodo-5-methoxyphe nyl)acetate |
| 5-I-RTX |
| 5'-Iodoresiniferatoxin |
| Benzeneacetic acid, 4-hydroxy-3-iodo-5-methoxy-, [(3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[4',5':5,6]benzo[1,2-d]-1,3-dioxol-5-yl]methyl ester |
| [(1R,2R,6R,10S,11R,15R,17R)-13-Benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo[11.4.1.0.0.0]octadeca-3,8-dien-8-yl]methyl (4-hydroxy-3-iodo-5-methoxyphenyl)acetate |