Orthocaine

Modify Date: 2024-01-02 06:48:17

Orthocaine structure	Common Name	Orthocaine
	CAS Number	536-25-4	Molecular Weight	167.162
	Density	1.3±0.1 g/cm3	Boiling Point	326.8±27.0 °C at 760 mmHg
	Molecular Formula	C₈H₉NO₃	Melting Point	141-143ºC
	MSDS	USA	Flash Point	151.4±23.7 °C

Use of Orthocaine

Orthocaine is a local anesthetic agent (extracted from patent WO2002089849A1)[1].

Name	Methyl 3-amino-4-hydroxybenzoate
Synonym	More Synonyms

Description	Orthocaine is a local anesthetic agent (extracted from patent WO2002089849A1)[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Gary W. Cleary, et al. Compositions and delivery systems for administration of a local anesthetic agent. Patent WO2002089849A1.

Density	1.3±0.1 g/cm3
Boiling Point	326.8±27.0 °C at 760 mmHg
Melting Point	141-143ºC
Molecular Formula	C₈H₉NO₃
Molecular Weight	167.162
Flash Point	151.4±23.7 °C
Exact Mass	167.058243
PSA	72.55000
LogP	0.92
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.606

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG2750000

CHEMICAL NAME :: Benzoic acid, 3-amino-4-hydroxy-, methyl ester

CAS REGISTRY NUMBER :: 536-25-4

BEILSTEIN REFERENCE NO. :: 0608715

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H9-N-O3

MOLECULAR WEIGHT :: 167.18

WISWESSER LINE NOTATION :: ZR DQ EVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935

Hazard Codes	Xi
Risk Phrases	22
HS Code	2922509090

Methyl 3-nitro-...

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~97%

Orthocaine

CAS#:536-25-4

Literature: Ackermann, Jean; Bleicher, Konrad; Ceccarelli, Simona M.; Chomienne, Odile; Mattei, Patrizio; Sander, Ulrike Obst Patent: US2007/191603 A1, 2007 ; Location in patent: Page/Page column 25 ;

Methanol

CAS#:67-56-1

3-Amino-4-hydro...

CAS#:1571-72-8

~10%

Orthocaine

CAS#:536-25-4

Literature: ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA Patent: WO2004/87714 A1, 2004 ; Location in patent: Page 53 ; WO 2004/087714 A1

Methanol

CAS#:67-56-1

4-Hydroxy-3-nit...

CAS#:616-82-0

~92%

Orthocaine

CAS#:536-25-4

Literature: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. Patent: WO2004/7491 A1, 2004 ; Location in patent: Page 75 ;

Acetyl chloride

CAS#:75-36-5

3-Amino-4-hydro...

CAS#:1571-72-8

~99%

Orthocaine

CAS#:536-25-4

Literature: ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA Patent: WO2005/34941 A1, 2005 ; Location in patent: Page/Page column 19 ;

(Trimethylsilyl...

CAS#:18107-18-1

3-Amino-4-hydro...

CAS#:1571-72-8

~52%

Orthocaine

CAS#:536-25-4

Literature: MEDIVIR AB Patent: WO2007/144379 A1, 2007 ; Location in patent: Page/Page column 43 ;

4-Hydroxy-3-nit...

CAS#:616-82-0

Orthocaine

CAS#:536-25-4

Literature: Journal of Organic Chemistry, , vol. 71, # 17 p. 6374 - 6381

Methyl 3-nitro-...

CAS#:99-42-3

N,N-Diethylaniline

CAS#:91-66-7

~8%

METHYL 2-METHYL...

CAS#:136663-21-3

Orthocaine

CAS#:536-25-4

Literature: Heterocycles, , vol. 64, p. 193 - 198

3-Amino-4-hydro...

CAS#:1571-72-8

Orthocaine

CAS#:536-25-4

Literature: Archiv der Pharmazie, , vol. 341, # 6 p. 386 - 392

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Aminobenz

Methyl 3-amino-4-hydroxybenzoate

2-amino-4-methoxycarbonylphenol

MFCD00017095

Orthoform

BENZOIC ACID,3-AMINO-4-HYDROXY-,METHYL ESTER

Orthoform New

Orthoderm

Orthocaine

Methyl m-amino-p-hydroxybenzoate

Methyl 4-hydroxy-3-aminobenzoate

Benzoic acid, 3-amino-4-hydroxy-, methyl ester

Methyl3-Amino-4-hydroxybenzoate

4-hydroxy-3-amino-benzoic acid methyl ester

3-Amino-4-hydroxybenzoic acid methyl ester

EINECS 208-627-3

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Orthocaine
Price: Click To Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Orthocaine
Price: ￥656.0/5g ￥2286.0/25g ￥1056.0/10g ￥216.0/1g
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Orthocaine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Methyl 3-amino-4-hydroxybenzoate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥350/500 mg

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Orthocaine

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