neorauflavane

Modify Date: 2024-01-10 16:31:04

neorauflavane Structure
neorauflavane structure
Common Name neorauflavane
CAS Number 53734-74-0 Molecular Weight 354.40
Density 1.3±0.1 g/cm3 Boiling Point 552.9±50.0 °C at 760 mmHg
Molecular Formula C21H22O5 Melting Point N/A
MSDS N/A Flash Point 288.2±30.1 °C

 Use of neorauflavane


Neorauflavane is a potent tyrosinase inhibitor derived from Campylotropis hirtella, with an IC50 value of 30 nM for tyrosinase monophenolase activity and an IC50 value of 500 nM for diphenolase activity. Neorauflavane can effectively reduce the melanin content of B16 melanoma cells[1].

 Names

Name N-Methyl-1,3-diphenyl-2-propanamine
Synonym More Synonyms

 neorauflavane Biological Activity

Description Neorauflavane is a potent tyrosinase inhibitor derived from Campylotropis hirtella, with an IC50 value of 30 nM for tyrosinase monophenolase activity and an IC50 value of 500 nM for diphenolase activity. Neorauflavane can effectively reduce the melanin content of B16 melanoma cells[1].
Related Catalog
References

[1]. Xuefei Tan, et al. Highly potent tyrosinase inhibitor, neorauflavane from Campylotropis hirtella and inhibitory mechanism with molecular docking. Bioorg Med Chem. 2016 Jan 15;24(2):153-9.   

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 552.9±50.0 °C at 760 mmHg
Molecular Formula C21H22O5
Molecular Weight 354.40
Flash Point 288.2±30.1 °C
Exact Mass 354.146729
PSA 68.15000
LogP 3.96
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.609

 Safety Information

Hazard Codes Xi

 Synonyms

4-[(7R)-5-Methoxy-2,2-dimethyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-7-yl]-1,3-benzenediol
1,3-Benzenediol, 4-[(7R)-7,8-dihydro-5-methoxy-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl]-