3-(Morpholinomethyl)indole

Modify Date: 2025-09-21 09:27:23

3-(Morpholinomethyl)indole Structure
3-(Morpholinomethyl)indole structure
Common Name 3-(Morpholinomethyl)indole
CAS Number 5379-88-4 Molecular Weight 216.27900
Density 1.206g/cm3 Boiling Point 379.6ºC at 760 mmHg
Molecular Formula C13H16N2O Melting Point N/A
MSDS N/A Flash Point 183.4ºC

 Names

Name 4-(1H-indol-3-ylmethyl)morpholine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.206g/cm3
Boiling Point 379.6ºC at 760 mmHg
Molecular Formula C13H16N2O
Molecular Weight 216.27900
Flash Point 183.4ºC
Exact Mass 216.12600
PSA 28.26000
LogP 1.93800
Index of Refraction 1.645

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NM1140000
CHEMICAL NAME :
Indole, 3-(morpholinomethyl)-
CAS REGISTRY NUMBER :
5379-88-4
BEILSTEIN REFERENCE NO. :
0193005
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H16-N2-O
MOLECULAR WEIGHT :
216.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
55 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,130,1952

 Synthetic Route

~82%

3-(Morpholinomethyl)indole Structure

3-(Morpholinome...

CAS#:5379-88-4

Literature: Hamid, M. Haniti S. A.; Allen, C. Liana; Lamb, Gareth W.; Maxwell, Aoife C.; Maytum, Hannah C.; et al. Journal of the American Chemical Society, 2009 , vol. 131, p. 1766 - 1774

~87%

3-(Morpholinomethyl)indole Structure

3-(Morpholinome...

CAS#:5379-88-4

Literature: Arzephoni, Amene Yaghoubi; Naimi-Jamal, M. Reza; Sharifi, Ali; Abaee, M. Saeed; Mirzaei, Mojtaba Journal of Chemical Research, 2013 , vol. 37, # 4 p. 216 - 218

~78%

3-(Morpholinomethyl)indole Structure

3-(Morpholinome...

CAS#:5379-88-4

Literature: Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721

~10%

3-(Morpholinomethyl)indole Structure

3-(Morpholinome...

CAS#:5379-88-4

Literature: Sakai, Norio; Shimamura, Kazuyori; Ikeda, Reiko; Konakahara, Takeo Journal of Organic Chemistry, 2010 , vol. 75, # 11 p. 3923 - 3926

~%

3-(Morpholinomethyl)indole Structure

3-(Morpholinome...

CAS#:5379-88-4

Literature: Matsumoto, Kiyoshi; Uchida, Takane; Hashimoto, Shiro; Yonezawa, Yukie; Iida, Hirokazu; et al. Heterocycles, 1993 , vol. 36, # 10 p. 2215 - 2220

~%

3-(Morpholinomethyl)indole Structure

3-(Morpholinome...

CAS#:5379-88-4

Literature: Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721

~%

3-(Morpholinomethyl)indole Structure

3-(Morpholinome...

CAS#:5379-88-4

Literature: Love, Brian E.; Nguyen, Binh T. Synlett, 1998 , # 10 p. 1123 - 1125

 Synonyms

3-Morpholinomethyl-indol
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