(+)-gamma-Tocopherol

Modify Date: 2024-01-02 15:15:50

(+)-gamma-Tocopherol structure	Common Name	(+)-gamma-Tocopherol
	CAS Number	54-28-4	Molecular Weight	416.68000
	Density	0.933g/cm3	Boiling Point	200 °C (0.1 mmHg)
	Molecular Formula	C₂₈H₄₈O₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	206ºC
	Symbol	GHS02, GHS06, GHS08	Signal Word	Danger

Use of (+)-gamma-Tocopherol

γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity[1].

Name	γ-tocopherol
Synonym	More Synonyms

Description	γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	Cyclooxygenase
In Vitro	γ-Tocopherol (D-γ-Tocopherol) is well absorbed and accumulates to a significant degree in some human tissues; it is metabolized, however, largely to 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman (gamma-CEHC), which is mainly excreted in the urine[1]. Plasma concentrations of γ-Tocopherol (D-γ-Tocopherol) are inversely associated with the incidence of cardiovascular disease and prostate cancer[1].
References	[1]. Q Jiang, et al. Gamma-Tocopherol, the Major Form of Vitamin E in the US Diet, Deserves More Attention. Am J Clin Nutr. 2001 Dec;74(6):714-22.

Density	0.933g/cm3
Boiling Point	200 °C (0.1 mmHg)
Molecular Formula	C₂₈H₄₈O₂
Molecular Weight	416.68000
Flash Point	206ºC
Exact Mass	416.36500
PSA	29.46000
LogP	8.53180
Index of Refraction	n20/D 1.505
Storage condition	2~8°C

(+)-gamma-Tocopherol MSDS(Chinese)

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	F
Risk Phrases	11-23/24/25-39/23/24/25
Safety Phrases	S24/25
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	3
HS Code	2932999099

Precursor 7
CAS#:119-13-1 (+)-Delta-Tocopherol CAS#:59-02-9 DL-alpha-Tocopherol CAS#:835613-31-5 6-O-acetyl-5-br... CAS#:835613-32-6 6-O-acetyl-5-fo...
CAS#:835613-33-7 6-O-acetyl--(2R... CAS#:34816-26-7 2-methyl-6-phyt... CAS#:75513-85-8 6-phytyltoluquinol
DownStream 5
CAS#:59-02-9 DL-alpha-Tocopherol CAS#:2668-47-5 2,6-ditert-buty... CAS#:23183-54-2 γ-chromanoxyl r... CAS#:7616-22-0 (±)-γ-Tocopherol
CAS#:6257-38-1 2,6-ditert-buty...

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Fine-scale thermal adaptation in a green turtle nesting population.

Proc. Biol. Sci. 279(1731) , 1077-84, (2012)

The effect of climate warming on the reproductive success of ectothermic animals is currently a subject of major conservation concern. However, for many threatened species, we still know surprisingly ...

Accumulation of γ- rather than α-tocopherol alters ethylene signaling gene expression in the vte4 mutant of Arabidopsis thaliana.

Plant Cell Physiol. 52 , 1389-1400, (2011)

Tocopherols are antioxidants found in chloroplasts of leaves, and it is a matter of current debate whether or not they can affect signaling and gene expression in plant cells. For insight into the pos...

Vitamin E isoforms directly bind PKCα and differentially regulate activation of PKCα.

Biochem. J. 441(1) , 189-198, (2012)

Vitamin E isoforms have opposing regulatory effects on leucocyte recruitment during inflammation. Furthermore, in vitro, vitamin E isoforms have opposing effects on leucocyte migration across endothel...

EINECS 200-201-5

D-gamma-Tocopherol

MFCD00066529

D-γ-Tocopherol

gamma-tocopherol