3,5-dichloropyridin-2-ol

Modify Date: 2025-08-23 17:11:44

3,5-dichloropyridin-2-ol Structure
3,5-dichloropyridin-2-ol structure
Common Name 3,5-dichloropyridin-2-ol
CAS Number 5437-33-2 Molecular Weight 163.989
Density 1.6±0.1 g/cm3 Boiling Point 293.9±35.0 °C at 760 mmHg
Molecular Formula C5H3Cl2NO Melting Point 180-182 °C(lit.)
MSDS Chinese USA Flash Point 131.5±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3,5-Dichloro-2-pyridinol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 293.9±35.0 °C at 760 mmHg
Melting Point 180-182 °C(lit.)
Molecular Formula C5H3Cl2NO
Molecular Weight 163.989
Flash Point 131.5±25.9 °C
Exact Mass 162.959167
PSA 32.86000
LogP 1.37
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.602
InChIKey ZICOPWJJZSJEDL-UHFFFAOYSA-N
SMILES O=c1[nH]cc(Cl)cc1Cl

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1146300
CHEMICAL NAME :
2(1H)-Pyridone, 3,5-dichloro-
CAS REGISTRY NUMBER :
5437-33-2
LAST UPDATED :
199710
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H3-Cl2-N-O
MOLECULAR WEIGHT :
163.99
WISWESSER LINE NOTATION :
T6MVJ CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#05400

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UV1146300
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 3,5-dichloropyridin-2-olBioassay

View more

Name: Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay
Source: 24386
Target: N/A
External Id: Sarm1 TIR NADase inhibitors
Name: Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL4296192
Name: Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA...
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL4296783
Name: Antibacterial activity against Acinetobacter baumannii ATCC 19606 (CO-ADD:GN_034); MI...
Source: ChEMBL
Target: Acinetobacter baumannii
External Id: CHEMBL4296193
Name: Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC...
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL4296187
Name: Antifungal activity against Cryptococcus neoformans H99 ATCC 208821 (CO-ADD:FG_002); ...
Source: ChEMBL
Target: Cryptococcus neoformans
External Id: CHEMBL4296190
Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2
Name: Antifungal activity against Candida albicans ATCC 90028 (CO-ADD:FG_001); MIC in YNB m...
Source: ChEMBL
Target: Candida albicans
External Id: CHEMBL4296189
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600
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 Synonyms

EINECS 226-609-3
3,5-dichloro-1,2-dihydropyridin-2-one
3,5-Dichloro-2(1H)-pyridinone
3,5-dichloropyridin-2-ol
3,5-Dichloropyridin-2(1H)-one
3,5-dichloro-1H-pyridin-2-one
MFCD00015401
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