2-pyridone

Modify Date: 2026-07-01 11:01:09

2-pyridone Structure
2-pyridone structure
Common Name 2-pyridone
CAS Number 142-08-5 Molecular Weight 95.099
Density 1.1±0.1 g/cm3 Boiling Point 323.7±15.0 °C at 760 mmHg
Molecular Formula C5H5NO Melting Point 105-107 °C(lit.)
MSDS Chinese USA Flash Point 181.1±5.3 °C
Symbol GHS06
GHS06
Signal Word Danger

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name pyridin-2-ol
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.1±0.1 g/cm3
Boiling Point 323.7±15.0 °C at 760 mmHg
Melting Point 105-107 °C(lit.)
Molecular Formula C5H5NO
Molecular Weight 95.099
Flash Point 181.1±5.3 °C
Exact Mass 95.037117
PSA 33.12000
LogP -0.58
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.514
Storage condition Store at RT.

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1144050
CHEMICAL NAME :
2(1H)-Pyridone
CAS REGISTRY NUMBER :
142-08-5
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H5-N-O
MOLECULAR WEIGHT :
95.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 93,143,1953 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
594 mg/kg/5D-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 85,173,1996

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements Missing Phrase - N15.00950417-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR UN2811
WGK Germany 3
RTECS UV1144050
Packaging Group III
Hazard Class 6.1
HS Code 2933399090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles39

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Steroidal Saponins from the Mesocarp of the Fruits of Raphia farinifera (Arecaceae) and their Cytotoxic Activity.

Nat. Prod. Commun. 10 , 1941-4, (2016)

Eight steroidal saponins (1-8), including one previously unreported derivative (1), have been isolated from the mesocarp of Raphia farinifera fruits by combined column chromatography and RP-HPLC metho...

Self-assembled hybrid metal oxide base catalysts prepared by simply mixing with organic modifiers.

Nat. Commun. 6 , 8580, (2015)

Multidentate materials formed by simply mixing heterogeneous and homogeneous components are promising for construction of versatile active sites on the surface of heterogeneous compounds, however, to ...

Janus kinase signaling activation mediates peritoneal inflammation and injury in vitro and in vivo in response to dialysate.

Kidney Int. 86(6) , 1187-96, (2014)

Peritoneal membrane pathology limits long-term peritoneal dialysis (PD). Here, we tested whether JAK/STAT signaling is implicated and if its attenuation might be salutary. In cultured mesothelial cell...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

pyridinol
2-PYRIDON
pyridinyl-6'-ol
2(1H)-Pyridone
2-oxypyridine
A-PYRIDONE
2-pyridone
2-hydroxy-pyridine
2-pyridinone
EINECS 205-520-3
2-PYRIDOL
Pyridin-2(1H)-one
2-pyridinol
pyridinone
Pyridone-2
2(1H)-Pyridinone
2-Oxopyridine
AURORA KA-3075
pyridone
2-Hydroxypyridine
pyridin-2-ol
1H-2-Pyridone
MFCD00006268

 2-pyridone | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the LogP of pyridin-2-ol?
A: LogP of pyridin-2-ol is -0.58.
Q: What is the polar surface area (PSA) of pyridin-2-ol?
A: Polar surface area (PSA) of pyridin-2-ol is 33.12000.
Q: What is the boiling point of pyridin-2-ol?
A: Boiling point of pyridin-2-ol is 323.7±15.0 °C at 760 mmHg.
Q: What English synonyms does pyridin-2-ol have?
A: English synonyms of pyridin-2-ol: pyridinol, 2-PYRIDON, pyridinyl-6'-ol, 2(1H)-Pyridone, 2-oxypyridine, A-PYRIDONE, 2-pyridone, 2-hydroxy-pyridine, 2-pyridinone, EINECS 205-520-3, 2-PYRIDOL, Pyridin-2(1H)-one, 2-pyridinol, pyridinone, Pyridone-2, 2(1H)-Pyridinone, 2-Oxopyridine, AURORA KA-3075, pyridone, 2-Hydroxypyridine, pyridin-2-ol, 1H-2-Pyridone, MFCD00006268.
Q: What is the CAS number of pyridin-2-ol?
A: CAS number of pyridin-2-ol is 142-08-5.
Q: What is the English name of pyridin-2-ol?
A: The English name of pyridin-2-ol is pyridin-2-ol.
Q: What is the molecular weight of pyridin-2-ol?
A: Molecular weight of pyridin-2-ol is 95.099.
Q: What are the storage conditions for pyridin-2-ol?
A: Storage conditions for pyridin-2-ol: Store at RT.
Q: What is the molecular formula of pyridin-2-ol?
A: Molecular formula of pyridin-2-ol is C5H5NO.
Q: What is the melting point of pyridin-2-ol?
A: Melting point of pyridin-2-ol is 105-107 °C(lit.).

 2-pyridonefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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