2-(1H-Indol-3-yl)acetohydrazide

Modify Date: 2024-01-11 06:41:24

2-(1H-Indol-3-yl)acetohydrazide Structure
2-(1H-Indol-3-yl)acetohydrazide structure
Common Name 2-(1H-Indol-3-yl)acetohydrazide
CAS Number 5448-47-5 Molecular Weight 189.214
Density 1.3±0.1 g/cm3 Boiling Point 518.0±33.0 °C at 760 mmHg
Molecular Formula C10H11N3O Melting Point 142-145 °C(lit.)
MSDS Chinese USA Flash Point 267.1±25.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name indole-3-acetic acid hydrazide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 518.0±33.0 °C at 760 mmHg
Melting Point 142-145 °C(lit.)
Molecular Formula C10H11N3O
Molecular Weight 189.214
Flash Point 267.1±25.4 °C
Exact Mass 189.090210
PSA 70.91000
LogP 0.06
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.691

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL3600000
CHEMICAL NAME :
Indole-3-acetic acid, hydrazide
CAS REGISTRY NUMBER :
5448-47-5
BEILSTEIN REFERENCE NO. :
0170455
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H11-N3-O
MOLECULAR WEIGHT :
189.24
WISWESSER LINE NOTATION :
T56 BMJ D1VMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01105

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 22-36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NL3600000
HS Code 2933990090

 Synthetic Route

~98%

2-(1H-Indol-3-yl)acetohydrazide Structure

2-(1H-Indol-3-y...

CAS#:5448-47-5

Literature: NEUROPORE THERAPIES, INC.; WRASIDLO, Wolfgang Patent: WO2014/14937 A1, 2014 ; Location in patent: Paragraph 0115 ;

~97%

2-(1H-Indol-3-yl)acetohydrazide Structure

2-(1H-Indol-3-y...

CAS#:5448-47-5

Literature: Zhang, Ming-Zhi; Mulholland, Nick; Beattie, David; Irwin, Dianne; Gu, Yu-Cheng; Chen, Qiong; Yang, Guang-Fu; Clough, John European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 22 - 32

~%

2-(1H-Indol-3-yl)acetohydrazide Structure

2-(1H-Indol-3-y...

CAS#:5448-47-5

Literature: Journal of Medicinal Chemistry, , vol. 50, # 8 p. 1939 - 1957

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

EINECS 226-672-7
MFCD00005634
1H-Indole-3-acetic acid, hydrazide
2-(1H-Indol-3-yl)acetohydrazide