(-)-Isoproterenol tartrate

Modify Date: 2024-01-02 08:36:29

(-)-Isoproterenol tartrate Structure
(-)-Isoproterenol tartrate structure
Common Name (-)-Isoproterenol tartrate
CAS Number 54750-10-6 Molecular Weight 361.34400
Density N/A Boiling Point 417.5ºCat 760 mmHg
Molecular Formula C15H23NO9 Melting Point 80-83ºC
MSDS USA Flash Point 179.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of (-)-Isoproterenol tartrate


Isoproterenol tartrate, (-)- is a β-Adrenoceptor agonist; increases cytosolic cAMP.

 Names

Name (-)-isoproterenol (+)-bitartrate salt
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 417.5ºCat 760 mmHg
Melting Point 80-83ºC
Molecular Formula C15H23NO9
Molecular Weight 361.34400
Flash Point 179.7ºC
Exact Mass 361.13700
PSA 187.78000

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ8960000
CAS REGISTRY NUMBER :
54750-10-6
LAST UPDATED :
198912
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H17-N-O3.C4-H6-O6
MOLECULAR WEIGHT :
361.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3768 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 21,1,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
849 mg/kg
TOXIC EFFECTS :
Vascular - regional or general arteriolar or venous dilation
REFERENCE :
SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 21,1,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
135 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 21,1,1953

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Articles9

More Articles
Beta-adrenergic receptor activation facilitates induction of a protein synthesis-dependent late phase of long-term potentiation.

J. Neurosci. 25(13) , 3294-303, (2005)

Long-term potentiation (LTP) is activity-dependent enhancement of synaptic strength that can critically regulate long-term memory storage. Like memory, LTP exhibits at least two mechanistically distin...

Effects of noradrenaline on frequency tuning of rat auditory cortex neurons.

Eur. J. Neurosci. 9(4) , 833-47, (1997)

The selectivity of rat auditory cortex neurons for pure tone frequency was studied during and after ionophoretic application (5-40 nA) of noradrenaline in urethane-anaesthetized rats. The dominant eff...

[Effect of synaptically active substances on the hyperthermic effect of prostaglandin E2 in rats].

Biull. Eksp. Biol. Med. 91(3) , 304-5, (1981)

It was established in experiments on unanesthetized rats given intraventricular injections of drugs that hyperthermic effect of prostaglandin E2 (PGE2) was markedly weakened by administering clofelin ...

 Synonyms

(-Isoproterenol hydrogen tartrate salt
(-)-isoprenalinetartrate
isolevine
isoprenaline tartrate dihydrate
l-isoprenalinebitartrate
(-)-isoprenaline (+)-bitartrate salt
isopropylnoradrenalinebitartrate
isolevin
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