Siastatin B microbial

Modify Date: 2024-01-02 11:42:05

Siastatin B microbial Structure
Siastatin B microbial structure
Common Name Siastatin B microbial
CAS Number 54795-58-3 Molecular Weight 218.20700
Density 1.48g/cm3 Boiling Point 579.2ºC at 760 mmHg
Molecular Formula C8H14N2O5 Melting Point N/A
MSDS Chinese USA Flash Point 304.1ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Siastatin B
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.48g/cm3
Boiling Point 579.2ºC at 760 mmHg
Molecular Formula C8H14N2O5
Molecular Weight 218.20700
Flash Point 304.1ºC
Exact Mass 218.09000
PSA 118.89000
Index of Refraction 1.581

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM6125400
CHEMICAL NAME :
3-Piperidinecarboxylic acid, 6-(acetylamino)-4,5-dihydroxy-, (3S-(3-alpha,4-alpha,5-alpha,6- beta))-
CAS REGISTRY NUMBER :
54795-58-3
LAST UPDATED :
199206
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H14-N2-O5
MOLECULAR WEIGHT :
218.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,963,1974

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
RIDADR NONH for all modes of transport
RTECS TM6125400
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles16

More Articles
Contributions of NanI sialidase to Caco-2 cell adherence by Clostridium perfringens type A and C strains causing human intestinal disease.

Infect. Immun. 82(11) , 4620-30, (2014)

Previous studies showed that Clostridium perfringens type D animal disease strain CN3718 uses NanI sialidase for adhering to enterocyte-like Caco-2 cells. The current study analyzed whether NanI is si...

Syntheses and activities of N-substituted derivatives of siastatin B.

J. Antibiot. 45(10) , 1662-8, (1992)

N-Substituted derivatives of siastatin B have been obtained by a chemical modification. Some derivatives showed potent inhibitory activities against Streptococcus sp. and Clostridium perfringens neura...

Synthesis of 3-episiastatin B analogues having anti-influenza virus activity.

J. Antibiot. 46(12) , 1883-9, (1993)

Two epimers of siastatin B, 3-episiastatin B (3) and 3,4-diepisiastatin B (4), were obtained by the chemical modification of siastatin B. Compound 3 showed marked inhibitory activity against influenza...

 Synonyms

(3S,4S,5R,6R)-6-acetamido-4,5-dihydroxypiperidine-3-carboxylic acid