Violacein
Violacein structure
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Common Name | Violacein | ||
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| CAS Number | 548-54-9 | Molecular Weight | 343.34 | |
| Density | 1.549g/cm3 | Boiling Point | 821.4ºC at 760mmHg | |
| Molecular Formula | C20H13N3O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 450.6ºC | |
Use of ViolaceinViolacein, a secondary metabolite produced by several microorganisms, possesses potent anticancer and low side effects. Violacein possesses antioxidant properties. Apoptosis inducer[1][2]. |
| Name | Violacein |
|---|---|
| Synonym | More Synonyms |
| Description | Violacein, a secondary metabolite produced by several microorganisms, possesses potent anticancer and low side effects. Violacein possesses antioxidant properties. Apoptosis inducer[1][2]. |
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| Related Catalog | |
| Target |
Microbial Metabolite |
| In Vitro | Violacein (0.25-3 µM; 24h; HCT116 and HT29 cells) possesses anticancer activity in both 2D and 3D cell models[1]. Violacein decreases RTKs expression and disturbs signaling pathways in CRC cells[1]. Cell Viability Assay[1]. Cell Line: HCT116 and HT29 (1.8 × 104 cells/well-100 µL) cells. Concentration: 0.25, 0.5, 1.0, 1.5, 2.0, 2.5, and 3.0 µM. Incubation Time: 24h. Result: In the 2D culture model, the violacein treatment reduced the cell viability, since there was a decrease in formazan production in the HT29 and HCT116 cell lines. Moreover, HT29 was more sensitive to violacein, as evidenced by the IC50 value (0.6 μM) compared to HCT116 (1.2 μM). |
| References |
| Density | 1.549g/cm3 |
|---|---|
| Boiling Point | 821.4ºC at 760mmHg |
| Molecular Formula | C20H13N3O3 |
| Molecular Weight | 343.34 |
| Flash Point | 450.6ºC |
| Exact Mass | 343.09600 |
| PSA | 101.20000 |
| LogP | 3.11110 |
| Index of Refraction | 1.804 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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