Ulodesine
Modify Date: 2026-07-01 10:44:35
Ulodesine structure
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Common Name | Ulodesine | ||
|---|---|---|---|---|
| CAS Number | 548486-59-5 | Molecular Weight | 264.28000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H16N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UlodesineUlodesine is a purine nucleoside phosphorylase (PNP) inhibitor. Ulodesine inhibits PNP with IC50 value of 2.293 nM/L. Ulodesine can be used for the research of hyporucicemia[1][2]. |
| Name | 7-[[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | Ulodesine is a purine nucleoside phosphorylase (PNP) inhibitor. Ulodesine inhibits PNP with IC50 value of 2.293 nM/L. Ulodesine can be used for the research of hyporucicemia[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Ulodesine (i.v.) potently inhibits PNP with IC50 value of 2.293 nM/L[1]. Ulodesine (i.v.) eliminates uric acid accumulations in blood of the mouse model[1]. |
| Molecular Formula | C12H16N4O3 |
|---|---|
| Molecular Weight | 264.28000 |
| Exact Mass | 264.12200 |
| PSA | 105.50000 |
| InChIKey | AFNHHLILYQEHKK-BDAKNGLRSA-N |
| SMILES | O=c1[nH]cnc2c(CN3CC(O)C(CO)C3)c[nH]c12 |
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Name: Inhibition of human PNP
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL931720
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Name: Experimentally measured binding affinity data (Ki) for protein-ligand complexes deriv...
Source: Shanghai Institute of Organic Chemistry
Target: N/A
External Id: PDBbind-Ki for protein-ligand complexes
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Name: Inhibition of human PNP by xanthine-oxidase coupled assay
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL951777
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Name: Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow ...
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL982802
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Name: Inhibition of bovine PNP
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL931721
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Name: Binding affinity to human PNP assessed as inhibition constant by TR-FRET assay
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL5551563
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Name: Inhibition of Plasmodium falciparum PNP
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL931722
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Name: Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assay
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL982801
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Name: Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition...
Source: ChEMBL
Target: Purine nucleoside phosphorylase
External Id: CHEMBL982800
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1
| DADMe-ImmH,7 |
| BCX 4208 |
| ULODESINE |
| 1n3i |
| DADMe-immucillin H |