Dapansutrile
Modify Date: 2024-01-09 00:16:37
Dapansutrile structure
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Common Name | Dapansutrile | ||
|---|---|---|---|---|
| CAS Number | 54863-37-5 | Molecular Weight | 133.17 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C4H7NO2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DapansutrileDapansutrile (OLT1177) is a potent, selective and orally active inhibitor of NLRP3 inflammasome. Anti-inflammatory, analgesic activity[1]. |
| Name | 3-(Methylsulfonyl)propanenitrile |
|---|---|
| Synonym | More Synonyms |
| Description | Dapansutrile (OLT1177) is a potent, selective and orally active inhibitor of NLRP3 inflammasome. Anti-inflammatory, analgesic activity[1]. |
|---|---|
| Related Catalog | |
| Target |
NLRP3 inflammasome[1] |
| References |
| Molecular Formula | C4H7NO2S |
|---|---|
| Molecular Weight | 133.17 |
| Exact Mass | 133.02000 |
| PSA | 66.31000 |
| LogP | 1.02548 |
| Storage condition | 2-8℃ |
|
~%
Dapansutrile CAS#:54863-37-5 |
| Literature: Kjaer et al. Acta Chemica Scandinavica (1947-1973), 1953 , vol. 7, p. 1370,1373 |
|
~88%
Dapansutrile CAS#:54863-37-5 |
| Literature: OLATEC INDUSTRIES LLC; ST. LAURENT, Joseph P.; JONES, Gerald S.; BRESSE, David M. Patent: US2013/225865 A1, 2013 ; Location in patent: Paragraph 0056-0058 ; |
|
~94%
Dapansutrile CAS#:54863-37-5 |
| Literature: Bell, Richard; Cottam, Peter D.; Davies, John; Jones, D. Neville Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , # 7 p. 2106 - 2115 |
|
~%
Dapansutrile CAS#:54863-37-5 |
| Literature: Rao, B. Dharma; Sarathi, T.V.N. Partha; Annapurna; Vani Journal of Sulfur Chemistry, 2011 , vol. 32, # 3 p. 263 - 272 |
| 2-methyl-2H-isoindole-1-carbonitrile |
| 2H-Isoindole-1-carbonitrile,2-methyl |
| 1-cyano-2-methylisoindole |
| 3-methanesulfonylpropionitrile |
| 3-(methylsulfonyl)propionitrile |
| 1-cyano-2-methylsulphonylethane |